Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618485 | 0.91 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9694981 | 0.88 | ERN1 (0.41) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9695928 | 0.88 | KDM4E (0.43) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9695046 | 0.86 | MAPT (0.53) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL5618611 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9695445 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL5617520 | 0.85 | MAPT (0.55) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9695076 | 0.84 | BRD4 (0.53) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL9695117 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL5618509 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | claimed |
| JP-2157273-A | — | — | None | — | — | JP | disclosed |
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | disclosed |
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | disclosed |
| US-5100914-A | Monoamine Oxidase Inhibitors, Central Nervous System Disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| JP-H02157273-A | ARYLALKOXYCOUMARIN, ITS PRODUCTION AND THERAPEUTIC AGENT CONTAINING THE SAME | BASF AG | 1990-06-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | ALDH1A1 664/4885HPGD 1525/4885MAPT 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.