Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9096650 | 0.99 | GCK (0.45) | GCKATP4AATP4BHTTSMN1; SMN2 | |
| SCHEMBL5423755 | 0.84 | GCK (0.46) | GCKATP4AATP4BHTTSMN1; SMN2 | |
| SCHEMBL2189993 | 0.80 | ATP4A (0.60) | ATP4AATP4BHTTSMN1; SMN2STAT3 | |
| SCHEMBL21636964 | 0.79 | HTT (0.44) | GCKATP4AATP4BHTTSMN1; SMN2 | |
| SCHEMBL5425817 | 0.77 | BRD4 (0.51) | ATP4AATP4BHTTSMN1; SMN2STAT3 | |
| SCHEMBL31309505 | 0.77 | GRM5 (0.53) | SMN1; SMN2MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL25151340 | 0.77 | STAT3 (0.47) | GCKATP4AATP4BHTTSMN1; SMN2 | |
| SCHEMBL2194287 | 0.76 | PPARG (0.50) | ATP4AATP4BHTTSMN1; SMN2MAPT | |
| SCHEMBL24169608 | 0.76 | RHEB (0.46) | GCKHTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL9746834 | 0.76 | PPARG (0.50) | ATP4AATP4BMAPTHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189736-B2 | Prodrugs of imidazopyridine derivatives | ALTANA PHARMA AG (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7141567-B2 | Polysubstituted imidazopyridines as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2006-11-28 | — | — | US | disclosed |
| EP-1313739-B1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| EP-1286993-B1 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2006-06-07 | — | — | EP | disclosed |
| EP-1313740-B1 | PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2005-11-30 | — | — | EP | disclosed |
| US-6916825-B2 | Alkylated imidazopyridine derivatives | ALTANA PHARMA AG (DE) | 2005-07-12 | — | — | US | disclosed |
| US-6869949-B2 | Polysubstituted imidazopyridines as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2005-03-22 | — | — | US | disclosed |
| US-20040214852-A1 | Polysubstituted imidazopyridines | ALTANA PHARMA AG (DE) | 2004-10-28 | — | — | US | disclosed |
| US-20040198764-A1 | Prodrugs of imidazopyridine derivatives | SENN-BILFINGER JORG (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040106642-A1 | POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-1286993-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA Pharma AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002034749-A1 | POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-02 | — | — | WO | disclosed |
| WO-2001072754-A1 | ALKYLATED IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072748-A1 | IMIDAZOPYRIDIN-8-ONES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072756-A1 | PRODRUGS OF IMIDAZOPYRIDINE DERIVATIVES | ALTANA PHARMA AG (DE) | 2001-10-04 | — | — | WO | disclosed |
| EP-0299470-B1 | Imidazo[1,2-a]pyridines | BYK GULDEN LOMBERG CHEM FAB (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5112834-A | Antisecretory and antiulcer | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0370056-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1990-05-30 | — | — | EP | disclosed |
| WO-1989000570-A1 | NEW DIAZOLS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299470-A1 | Imidazo[1,2-a]pyridines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106642-A1 | POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS | GIPR, SLC10A2, VIP | GCK 197/4885ATP4A 82/4885ATP4B 162/4885 |
| US-20040198764-A1 | Prodrugs of imidazopyridine derivatives | SI, CYP2E1, UGT1A1 | GCK 472/4885ATP4A 518/4885ATP4B 1271/4885 |
| US-20040214852-A1 | Polysubstituted imidazopyridines | GIPR, VIP, SLC10A2 | GCK 310/4885ATP4A 89/4885ATP4B 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.