Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945017 | 1.00 | KIF11 (0.39) | KIF11HDAC2PDE4APDE4BPDE4C | |
| SCHEMBL14458019 | 0.95 | PDE4A (0.40) | KIF11HDAC2PDE4APDE4BPDE4C | |
| SCHEMBL14457993 | 0.81 | IKBKB (0.35) | KIF11PARP1PARP2KDM4EALDH1A1 | |
| SCHEMBL14458020 | 0.80 | PDE4A (0.43) | HDAC2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4148437 | 0.78 | GRIN2B (0.49) | KIF11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5889322 | 0.78 | GRIN2B (0.49) | KIF11PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10252171 | 0.78 | IKBKB (0.45) | HDAC2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14458014 | 0.76 | ESR2 (0.51) | HDAC2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22201144 | 0.76 | PARP1 (0.48) | KIF11HDAC2PDE4APDE4BPDE4C | |
| SCHEMBL22190351 | 0.76 | PARP1 (0.48) | KIF11HDAC2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | AR, NR5A1, SRD5A1 | KIF11 3938/4885HDAC2 2642/4885PDE4A 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.