Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148437 | 1.00 | GRIN2B (0.49) | GRIN2BL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL5620504 | 0.96 | GRIN2B (0.46) | GRIN2BL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL14458017 | 0.89 | AR (0.43) | GRIN2BL3MBTL1GRM2MMP2MMP9 | |
| SCHEMBL13945021 | 0.88 | PDE4A (0.40) | GRIN2BL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL14474703 | 0.88 | PDE4A (0.40) | GRIN2BL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL14063609 | 0.82 | DRD2 (0.40) | GRIN2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14458018 | 0.80 | CRBN (0.40) | PDE4APDE4BPDE4CPDE4DACHE | |
| SCHEMBL5620196 | 0.78 | KIF11 (0.39) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL13945017 | 0.78 | KIF11 (0.39) | PDE4APDE4BPDE4CPDE4DKIF11 | |
| SCHEMBL14458012 | 0.77 | POLB (0.57) | PDE4APDE4BPDE4CPDE4DNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7122506-B2 | Cyclic imines as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1077938-B1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-20040186287-A1 | Cyclic imines as pesticides | PLANT ANDREW (DE) | 2004-09-23 | — | — | US | disclosed |
| EP-1080072-B1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-08-04 | — | — | EP | disclosed |
| US-6770595-B2 | ACTIVITY AGAINST ARTHROPODS IN AGRICULTURE AND PARASITES ENCOUNTERED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
| US-6632833-B1 | Their preparation and to their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| US-6399771-B1 | AGRICULTURE; VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-04 | — | — | US | disclosed |
| US-6274613-B1 | APPLYING COMPOUNDS SUCH AS A GAMMA-ETHOXY-GAMMA-BUTYROLACTAM TO PESTS AND/OR THEIR HABITATS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | disclosed |
| EP-1121357-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1080072-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2001-03-07 | — | — | EP | disclosed |
| EP-1077938-A1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000021958-A1 | 2-HETARYL-3,4-DIHYDRO-2H-PYRROLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999059967-A1 | 2-(2-METHYLPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999059968-A1 | 2-(2-CHLOROPHENYL)-3,4-DIHYDRO-2H-PYRROL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0942901-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022438-A1 | CYCLIC IMINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | CYP2F1, HK1, FBP1 | GRIN2B 1519/4885L3MBTL1 4328/4885PDE4A 3966/4885 |
| US-20040186287-A1 | Cyclic imines as pesticides | DDT, CYP1A1, AR | GRIN2B 654/4885L3MBTL1 1810/4885PDE4A 743/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | GRIN2B 1588/4885L3MBTL1 224/4885PDE4A 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.