Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.86 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.86 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.86 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.86 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.86 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.86 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.86 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.86 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.86 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.86 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.86 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.86 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.86 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.86 |
| ▸ | CYP4F8 | P98187 | 2/20 | 0.86 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743214 | 0.93 | CYP1A1 (1.00) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL29489425 | 0.93 | CYP3A4 (0.73) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL196765 | 0.93 | CYP3A4 (0.73) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.90 | CYP3A4 (0.70) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.90 | CYP3A4 (0.70) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL29628977 | 0.90 | CYP3A4 (0.77) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL1180343 | 0.88 | ABL1 (0.69) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL28102064 | 0.86 | CYP1A2 (0.72) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL458391 | 0.86 | CYP1A1 (0.64) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL29740761 | 0.86 | CYP1A1 (0.64) | CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169797-B2 | Protein-tyrosine phosphatase inhibitors and uses thereof | ABBOTT LABORATORIES (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040214870-A1 | Controlling gene expression; antidiabetic agents; insulin resistance; autoimmune disease; 5-(3-((1E)-3-(3-hydroxy-2-(methoxycarbonyl)phenoxy)prop-1-enyl)phenyl)isoxazole-3-carboxylic acid | ABBVIE INC. | 2004-10-28 | — | — | US | disclosed |
| US-20040167188-A1 | Controlling gene expression; antidiabetic agents; insulin resistance; autoimmune disease; | ABBOTT LABORATORIES | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167188-A1 | Controlling gene expression; antidiabetic agents; insulin resistance; autoimmune disease; | G6PC1, PPP1R1B, PPP1R7 | CYP3A4 2929/4885CYP1A1 676/4885CYP1A2 1265/4885 |
| US-20040214870-A1 | Controlling gene expression; antidiabetic agents; insulin resistance; autoimmune disease; 5-(3-((1E)-3-(3-hydroxy-2-(methoxycarbonyl)phenoxy)prop-1-enyl)phenyl)isoxazole-3-carboxylic acid | G6PC1, PPP1R7, PPP1R1B | CYP3A4 2520/4885CYP1A1 872/4885CYP1A2 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.