Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | CYP2E1 | P05181 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | CYP2A6 | P11509 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | CYP4B1 | P13584 | 3/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 3/20 | 1.00 |
| ▸ | CYP3A5 | P20815 | 3/20 | 1.00 |
| ▸ | CYP2A7 | P20853 | 3/20 | 1.00 |
| ▸ | CYP3A7 | P24462 | 3/20 | 1.00 |
| ▸ | CYP2F1 | P24903 | 3/20 | 1.00 |
| ▸ | CYP2C18 | P33260 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 3/20 | 1.00 |
| ▸ | CYP2J2 | P51589 | 3/20 | 1.00 |
| ▸ | CYP4F2 | P78329 | 3/20 | 1.00 |
| ▸ | CYP4F8 | P98187 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620245 | 0.93 | CYP3A4 (0.86) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL26498789 | 0.91 | CYP1A1 (0.83) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL26498734 | 0.91 | CYP1A1 (0.83) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL26498639 | 0.91 | CYP1A1 (0.83) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL29628977 | 0.87 | CYP3A4 (0.77) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL8987283 | 0.85 | CYP1A1 (0.74) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL2407878 | 0.85 | CYP1A1 (0.74) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL21296972 | 0.85 | ABL1 (0.73) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL196765 | 0.84 | CYP3A4 (0.73) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL29489425 | 0.84 | CYP3A4 (0.73) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | CYP1A1 6/4885CYP1B1 2/4885CYP1A2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.