SCHEMBL562211

SCHEMBL562211

CCOC(CCC#N)OCC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
THRB P10828 1/20 0.35
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9139427 0.88 TSHR (0.46) TSHRMEN1KMT2ATHRBALDH1A1
SCHEMBL10393868 0.86 TSHR (0.44) TSHRMEN1KMT2ATHRBALDH1A1
SCHEMBL3635650 0.84 MEN1 (0.33) TSHRMEN1KMT2AALDH1A1
SCHEMBL15134519 0.81 TSHR (0.44) TSHRMEN1KMT2AALDH1A1TDP1
SCHEMBL1367526 0.76
SCHEMBL24587748 0.76 TSHR (0.39) TSHR
SCHEMBL16826455 0.76 TSHR (0.39) TSHR
SCHEMBL31578781 0.76 TSHR (0.50) TSHRALDH1A1
SCHEMBL24588713 0.76 TSHR (0.39) TSHR
SCHEMBL10805593 0.75 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128421-B Simple preparation method of 5-halogenated-7-azaindole 新发药业有限公司 2020-08-11 CN claimed
EP-4737436-A1 CATIONIC LIPID CONTAINING TWO TERTIARY AMINE GROUPS, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd (CN) 2026-05-06 EP disclosed
US-20250268828-A1 Lipid Nanoparticle Compositions for Delivering Circular Polynucleotides ORNA THERAPEUTICS, INC. 2025-08-28 US disclosed
WO-2025104695-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES THEREOF Corti Therapeutics Pte. Ltd. (SG) 2025-05-22 WO disclosed
CN-119698406-A Nanomaterials comprising triols 比姆医疗股份有限公司 2025-03-25 CN disclosed
CN-119562942-A Cationic lipid containing two tertiary amine groups and application thereof 厦门赛诺邦格生物科技股份有限公司 2025-03-04 CN disclosed
WO-2025001700-A1 CATIONIC LIPID CONTAINING TWO TERTIARY AMINE GROUPS, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2025-01-02 WO disclosed
US-20240358841-A1 NANOMATERIALS COMPRISING TETRAVALENT LIPID COMPOUNDS BEAM THERAPEUTICS INC. 2024-10-31 US disclosed
EP-4452930-A1 IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES Beam Therapeutics Inc. (US) 2024-10-30 EP disclosed
EP-4452942-A1 NANOMATERIALS COMPRISING DISULFIDES Beam Therapeutics Inc. (US) 2024-10-30 EP disclosed
US-5162308-A Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1992-11-10 US disclosed
EP-0486666-A1 THERAPEUTIC HETEROCYCLIC COMPOUNDS. WELLCOME FOUND (GB) 1992-05-27 EP disclosed
WO-1991018897-A1 THERAPEUTIC HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1991-12-12 WO disclosed
EP-0372263-A2 Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1990-06-13 EP disclosed
EP-0363255-A1 Analogues of 4-desoxydaunosamine, process for their preparation, anthracycline derivatives of these analogues and use of these anthracyclines as medicaments LABORATOIRES HOECHST S.A. (FR) 1990-04-11 EP disclosed
US-4855314-A VASOCONTRICTORS, TREATMENT OF MIGRAINES, 3-(AMINO-ETHYL)-5-(PHENYL(ALKYL)-CARBONYL OR SULFONYL-AMINOALKYL SUBSTITUTED GLAXO GROUP LIMITED (GB) 1989-08-08 US disclosed
EP-0240096-A1 Indole derivatives having a selective vasoconstrictor activity GLAXO GROUP LIMITED (GB) 1987-10-07 EP disclosed
EP-0050800-B1 CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1986-06-18 EP disclosed
EP-0050800-A1 Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1982-05-05 EP disclosed
US-4141915-A REACTING AN UNSATURATED NITRILE, AN ALCOHOL, AND CARBON MONOXIDE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358841-A1 NANOMATERIALS COMPRISING TETRAVALENT LIPID COMPOUNDS LCAT, PHOSPHO1, LIPC TSHR 1236/4885MEN1 1288/4885KMT2A 2241/4885
US-20250268828-A1 Lipid Nanoparticle Compositions for Delivering Circular Polynucleotides ABCB4, CETP, HDLBP TSHR 3689/4885MEN1 4042/4885KMT2A 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.