Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562211 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7811459 | 0.81 | LMNA (0.46) | MEN1KMT2ATSHRALDH1A1 | |
| Ethylene SCHEMBL10487157 | 0.79 | LMNA (0.43) | TSHRALDH1A1 | |
| SCHEMBL2853079 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL9139427 | 0.74 | TSHR (0.46) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL449954 | 0.73 | — | — | |
| SCHEMBL10393868 | 0.72 | TSHR (0.44) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL2853062 | 0.72 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL10393867 | 0.71 | LMNA (0.43) | TSHR | |
| SCHEMBL2847082 | 0.71 | TSHR (0.44) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146973-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008130953-A2 | 2-IMIN0IS0THIAZ0LE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-10-30 | — | — | WO | disclosed |