Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376201 | 0.85 | MTNR1A (0.46) | MTNR1ATP53RECQLMAPTGAA | |
| SCHEMBL25373829 | 0.83 | MTNR1A (0.44) | MTNR1ATP53RECQLMAPTGAA | |
| SCHEMBL27956975 | 0.82 | MTNR1A (0.55) | MTNR1ATP53RECQLMAPTIDO1 | |
| SCHEMBL657069 | 0.80 | MTNR1A (0.57) | MTNR1ATP53MAPTIDO1KDM1A | |
| SCHEMBL17996703 | 0.80 | MTNR1A (0.53) | MTNR1ATP53MAPTGAAIDO1 | |
| SCHEMBL18625858 | 0.78 | MTNR1A (0.51) | MTNR1AMAPTIDO1KDM1ASLC6A4 | |
| SCHEMBL19284721 | 0.78 | MTNR1A (0.54) | MTNR1ATP53MAPTIDO1KDM1A | |
| SCHEMBL31043018 | 0.76 | MTNR1A (0.45) | MTNR1ATP53RECQLMAPTGAA | |
| SCHEMBL11466368 | 0.76 | MTNR1A (0.49) | MTNR1AMAPTIDO1KDM1ASLC6A4 | |
| SCHEMBL30477104 | 0.76 | SLC6A4 (0.59) | MTNR1ATP53MAPTIDO1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509579-B2 | Thermoplastic resin and optical lens including same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2025-12-30 | — | — | US | disclosed |
| CN-115996931-B | Cyclic diol compound, process for producing the compound, and use of the compound | 新日本理化株式会社 | 2025-04-01 | — | — | CN | disclosed |
| US-20230399510-A1 | THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-14 | — | — | US | disclosed |
| EP-4239010-A1 | THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116323753-A | Thermoplastic resin and optical lens comprising the same | 三菱瓦斯化学株式会社 | 2023-06-23 | — | — | CN | disclosed |
| CN-115996931-A | Cyclic diol compound, process for producing the compound, and use of the compound | 新日本理化株式会社 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022091996-A1 | THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME | 三菱瓦斯化学株式会社 | 2022-05-05 | — | — | WO | disclosed |
| WO-2022091990-A1 | CYCLIC DIOL COMPOUND, PRODUCTION METHOD FOR SAID COMPOUND, AND USE OF SAID COMPOUND | 新日本理化株式会社 | 2022-05-05 | — | — | WO | disclosed |
| US-9593069-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-9593069-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-8722939-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722939-B2 | Cyclohexane-1,3-diones for use in the treatment of amyotrophic lateral sclerosis | NORTHWESTERN UNIVERSITY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130345420-A9 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST) | BUNCH LENNART (DK) | 2013-12-26 | — | — | US | disclosed |
| US-20120264765-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | CAMBRIA PHARMACEUTICALS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120264765-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | CAMBRIA PHARMACEUTICALS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120035361-A1 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST) | BUNCH LENNART (DK) | 2012-02-09 | — | — | US | disclosed |
| WO-2011059821-A2 | CYCLOHEXANE-1,3-DIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | CAMBRIA PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2010066253-A1 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1 /GLAST) | BUNCH, LENNART (DK) | 2010-06-17 | — | — | WO | disclosed |
| US-20070027150-A1 | 2-Amino-quinazolin-5-ones | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2007-02-01 | — | — | US | disclosed |
| US-20070027150-A1 | 2-Amino-quinazolin-5-ones | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035361-A1 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST) | SLC1A1, SLC1A2, SLC1A3 | MTNR1A 696/4885TP53 4828/4885RECQL 4587/4885 |
| US-12509579-B2 | Thermoplastic resin and optical lens including same | RIF1, POT1, LAS1L | MTNR1A 2129/4885TP53 2807/4885RECQL 403/4885 |
| US-20120264765-A1 | Cyclohexane-1,3-Diones for Use in the Treatment of Amyotrophic Lateral Sclerosis | SMN1; SMN2, HTT, CPT1B | MTNR1A 1267/4885TP53 4547/4885RECQL 527/4885 |
| US-20130345420-A9 | SELECTIVE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTER SUBTYPE 1 (EAAT1/GLAST) | SLC1A1, SLC1A2, SLC1A3 | MTNR1A 696/4885TP53 4828/4885RECQL 4587/4885 |
| US-20070027150-A1 | 2-Amino-quinazolin-5-ones | TK1, TK2, SLC1A5 | MTNR1A 776/4885TP53 41/4885RECQL 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.