SCHEMBL562589

SCHEMBL562589

Cc1cc(OCCC(C)(C)O)cc(C)c1-c1cccc(COc2ccc3c(c2)CC2(CC2)C3CC=O)c1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 14/20 0.39
FFAR1 O14842 6/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10203920 0.91 FFAR1 (0.43) CD274FFAR1
SCHEMBL563019 0.89 FFAR1 (0.38) CD274FFAR1
SCHEMBL13084425 0.88 FFAR1 (0.39) CD274FFAR1
SCHEMBL13092090 0.88 FFAR1 (0.36) CD274FFAR1
SCHEMBL562826 0.87 CD274 (0.36) CD274FFAR1
SCHEMBL13084459 0.87 CD274 (0.39) CD274FFAR1
SCHEMBL562645 0.87 FFAR1 (0.45) CD274FFAR1
SCHEMBL13092533 0.83 FFAR1 (0.33) CD274FFAR1
SCHEMBL10203766 0.82 CD274 (0.39) CD274FFAR1
SCHEMBL563079 0.81 CD274 (0.38) CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423176-A1 CARBOXYLIC ACID COMPOUND Astellas Pharma Inc. (JP) 2012-02-29 EP disclosed
US-20120035196-A1 CARBOXYLIC ACID COMPOUND ASTELLAS PHARMA INC. (JP) 2012-02-09 US disclosed
US-20120035196-A1 CARBOXYLIC ACID COMPOUND ASTELLAS PHARMA INC. (JP) 2012-02-09 US disclosed
US-20120035196-A1 CARBOXYLIC ACID COMPOUND ASTELLAS PHARMA INC. (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035196-A1 CARBOXYLIC ACID COMPOUND GPR119, GPR65, GPR55 CD274 3683/4885FFAR1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.