SCHEMBL562630

SCHEMBL562630

CC1(C)C2=CC(=O)C=CC2=Nc2ccc(O)cc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9225122 0.82 ESR2 (0.31) ESR2
SCHEMBL7873730 0.81 EHMT2 (0.40) ALDH1A1LMNACYP3A4PDE3BPDE3A
SCHEMBL8949339 0.81
SCHEMBL30434812 0.79 CASP3 (0.35) ALDH1A1LMNA
SCHEMBL30434937 0.79 CASP3 (0.35) ALDH1A1LMNA
SCHEMBL12209666 0.78 ALDH1A1 (0.32) ALDH1A1LMNACYP3A4
SCHEMBL3164641 0.77 ESR1 (0.52) ALDH1A1ESR1ESR2
SCHEMBL8949502 0.76 MAPK14 (0.31)
SCHEMBL29931019 0.71 PDE3B (0.31) ALDH1A1LMNACYP3A4PDE3BPDE3A
SCHEMBL16352729 0.71 ALDH1A1 (0.37) ALDH1A1LMNACYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008145830-A2 NOVEL PRO-FLUORESCENT COMPOUNDS QUIDD (FR) 2008-12-04 WO claimed
EP-0667397-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2001-10-04 EP claimed
EP-0667397-A1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1995-08-16 EP claimed
US-5393615-A Electrode with acridinone or dibenzoxazepinone mediator on surface MILES INC. (US) 1995-02-28 US claimed
JP-1131192-A None JP disclosed
EP-3753481-B1 TRANSIENT DECAY AMPEROMETRY DEVICE ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2024-07-17 EP disclosed
EP-2535703-B1 Multi-electrode biosensor system ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-11-03 EP disclosed
US-11091790-B2 Determining analyte concentration from variant concentration distribution in measurable species ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-08-17 US disclosed
EP-3369825-B1 POROUS PARTICLE REAGENT COMPOSITIONS AND DEVICES FOR BIOSENSORS ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-07-28 EP disclosed
CN-105603045-B Accuracy improving desiccant 安晟信医疗科技控股公司 2021-05-14 CN disclosed
US-10989683-B2 Identifying ionizable species with voltammetric duty cycles ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-04-27 US disclosed
EP-2499483-B1 Method and biosensor for assessing the volume of a blood sample ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-03-17 EP disclosed
US-4932871-A COUPLING A GLUCOSIDE TO A MALTOOLIGOSACCHARIDE MILES INC. (US) 1990-06-12 US disclosed
EP-0324912-A2 A rapid method for preparing chromogenic alfa-amylase substrate compounds at high preparative yields MILES INC. (US) 1989-07-26 EP disclosed
EP-0320752-A1 Analytical reagent mixing apparatus for performing sequential analytical reactions MILES INC. (US) 1989-06-21 EP disclosed
JP-H01131192-A CHROMOGENIC ACRIDINONE ENZYME SUBSTRATE AND ITS PRODUCTION MILES INC 1989-05-24 JP disclosed
US-4822747-A STABILIZATION IN AQUEOUS SOLUTION MILES INC. (US) 1989-04-18 US disclosed
US-4810636-A HYDROLASES, COLORIMETRIC ANALYSIS MILES INC. (US) 1989-03-07 US disclosed
EP-0270946-A2 Chromogenic acridinone enzyme substrates MILES INC. (US) 1988-06-15 EP disclosed
EP-0270937-A2 Stable immobilized hapten reagent for use in heterogeneous immunometric assays MILES INC. (US) 1988-06-15 EP disclosed