Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165781 | 0.77 | ESR1 (0.51) | ESR1ESR2ALDH1A1KDM4EMAPT | |
| SCHEMBL562630 | 0.77 | ALDH1A1 (0.33) | ESR1ESR2ALDH1A1 | |
| SCHEMBL9171997 | 0.71 | ESR2 (0.53) | ESR1ESR2MEN1KMT2AUSP2 | |
| SCHEMBL9225122 | 0.71 | ESR2 (0.31) | ESR2 | |
| SCHEMBL8949339 | 0.69 | — | — | |
| SCHEMBL8949502 | 0.65 | MAPK14 (0.31) | — | |
| SCHEMBL7876604 | 0.65 | PDE3B (0.43) | ESR1ESR2 | |
| SCHEMBL9166727 | 0.65 | ESR1 (0.38) | ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL8994244 | 0.64 | PDE3B (0.42) | ESR1ESR2ALDH1A1KDM4EPOLB | |
| SCHEMBL23767778 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590479-B1 | NUCLEIC ACID AMPLIFICATION | GE HEALTHCARE BIO SCIENCES (US) | 2010-11-24 | — | — | EP | disclosed |
| EP-1421213-B1 | LABELED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| US-7125671-B2 | Nucleic acid amplification with terminal-phosphate labeled nucleotides | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1590479-A4 | NUCLEIC ACID AMPLIFICATION | AMERSHAM BIOSCIENCES CORP (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1590479-A1 | NUCLEIC ACID AMPLIFICATION | Amersham Biosciences Corp. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004072304-A1 | NUCLEIC ACID AMPLIFICATION | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | disclosed |
| EP-0402699-B1 | Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates | MILES INC (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5183743-A | Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates | MILES INC. (US) | 1993-02-02 | — | — | US | disclosed |
| US-5104980-A | CHROMOGENIC DIBENZOXAZEPINONE AND DIBENZOTHIAZEPINONE ENZYME SUBSTRATES | MILES INC. (US) | 1992-04-14 | — | — | US | disclosed |