Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275398 | 0.93 | RAB9A (0.48) | PTGER1MRGPRX4MAPTALDH1A1MEN1 | |
| SCHEMBL6169074 | 0.92 | ERN1 (0.54) | PTGER1MRGPRX4ERN1MAPTCYP1A2 | |
| SCHEMBL5628445 | 0.85 | MRGPRX4 (0.51) | PTGER1MRGPRX4MAPTKDM4EALDH1A1 | |
| SCHEMBL14774805 | 0.81 | PTGER1 (0.52) | PTGER1MRGPRX4MAPTCYP1A2CYP2C9 | |
| SCHEMBL2284712 | 0.79 | ENPP2 (0.54) | MRGPRX4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5465784 | 0.78 | SLC6A4 (0.52) | PTGER1MRGPRX4MAPTKDM4EALDH1A1 | |
| SCHEMBL5627381 | 0.78 | PTGER1 (0.55) | PTGER1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1119150 | 0.78 | JAK2 (0.57) | PTGER1MRGPRX4MAPTKDM4EMEN1 | |
| SCHEMBL5627912 | 0.76 | PTGER1 (0.48) | PTGER1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL2288692 | 0.75 | SLC6A4 (0.53) | MRGPRX4MAPTALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082912-A1 | Pyrrole compounds for the treatment of prostaglandine mediated diseases | GLAXO GROUP LIMITED (GB) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082912-A1 | Pyrrole compounds for the treatment of prostaglandine mediated diseases | PTGER1, PTGDR, PTGIR | PTGER1 1/4885MRGPRX4 77/4885ERN1 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.