SCHEMBL5465784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5631333	0.88	MAOA (0.51)	CCR5ALDH1A1MAPTMAOAMAOB
	SCHEMBL29227218	0.85	CCR5 (0.56)	SLC6A4CCR5TACR2MAPTMAOA
	SCHEMBL1119150	0.85	JAK2 (0.57)	SLC6A4CCR5PTGER1TACR2SMN1; SMN2
	SCHEMBL5631282	0.83	TUBB1 (0.51)	CCR5TACR2ALDH1A1LMNASMN1; SMN2
	SCHEMBL17294040	0.82	SLC6A4 (0.57)	SLC6A4CCR5TACR2MAPTKMT2A
	SCHEMBL9947475	0.82	ALDH1A1 (0.47)	CCR5ALDH1A1SMN1; SMN2MAPTMAOA
	SCHEMBL12437548	0.82	MAOA (0.47)	SLC6A4CCR5SLC6A2SLC6A3ALDH1A1
	SCHEMBL275887	0.82	CCR5 (0.62)	CCR5ALDH1A1LMNASMN1; SMN2MAPT
	SCHEMBL30866193	0.82	CCR5 (0.62)	CCR5ALDH1A1LMNASMN1; SMN2MAPT
	SCHEMBL5628019	0.82	MAPT (0.51)	CCR5PTGER1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.