Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711229 | 0.90 | CAPN1 (0.58) | CAPN1CTSLCTSKCTSBCCR1 | |
| SCHEMBL7665098 | 0.84 | CMA1 (0.46) | CAPN1CTSLCTSKCTSBCTSD | |
| SCHEMBL7662824 | 0.84 | CTSD (0.49) | CAPN1ATMCTSLCTSKCTSB | |
| SCHEMBL7667089 | 0.82 | CTSL (0.53) | CAPN1CTSLCTSKCTSBCCR1 | |
| SCHEMBL7667094 | 0.82 | CTSL (0.53) | CAPN1CTSLCTSKCTSBCCR1 | |
| SCHEMBL5711352 | 0.80 | PREP (0.57) | CAPN1CTSLCTSKCTSBACE | |
| SCHEMBL7655857 | 0.79 | POLB (0.52) | CAPN1ATMCTSLCTSKCTSB | |
| SCHEMBL5711285 | 0.79 | CCR1 (0.50) | CAPN1CCR1ACE | |
| SCHEMBL5711367 | 0.77 | ACE (0.48) | CAPN1ACEPREPDPP4ALDH1A1 | |
| SCHEMBL5711242 | 0.77 | CCR1 (0.50) | CAPN1CCR1ACEPREPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |