Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943067 | 0.87 | TLR7 (0.35) | AGTR1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL5633422 | 0.83 | MAPT (0.43) | L3MBTL1ALDH1A1MAPTKMT2ACYP1A2 | |
| SCHEMBL5633330 | 0.82 | CDC25B (0.38) | L3MBTL1ALDH1A1MAPTCYP19A1BACE1 | |
| SCHEMBL5633433 | 0.82 | CDC25B (0.38) | L3MBTL1ALDH1A1MAPTCYP19A1BACE1 | |
| SCHEMBL5634034 | 0.82 | CDC25B (0.38) | L3MBTL1ALDH1A1MAPTCYP19A1BACE1 | |
| SCHEMBL5634058 | 0.80 | CDC25B (0.37) | L3MBTL1ALDH1A1MAPTCYP19A1BACE1 | |
| SCHEMBL30942760 | 0.79 | ADORA1 (0.32) | AGTR1L3MBTL1KMT2A | |
| SCHEMBL5634017 | 0.76 | AGTR1 (0.36) | AGTR1L3MBTL1TRPA1MMP1MMP3 | |
| SCHEMBL30943167 | 0.73 | ALDH1A1 (0.33) | L3MBTL1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL31721493 | 0.73 | KMT2A (0.32) | L3MBTL1MMP1MMP3MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123548-A1 | Pth agonists | COWAN DAVID J | 2007-05-31 | — | — | US | claimed |
| US-20070123548-A1 | Pth agonists | COWAN DAVID J | 2007-05-31 | — | — | US | disclosed |
| EP-1713782-A1 | PTH AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005077918-A1 | PTH AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123548-A1 | Pth agonists | PTH1R, SSTR3, CALCR | AGTR1 168/4885L3MBTL1 4667/4885TRPA1 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.