SCHEMBL563339

SCHEMBL563339

CN(C)/C=N/N=C/N(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
TSHR P16473 1/20 0.33
TAS2R38 P59533 1/20 0.33
BCAT1 P54687 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1528792 1.00 ALOX15 (0.33) ALOX15RECQLTSHRTAS2R38BCAT1
SCHEMBL31231602 1.00 ALOX15 (0.33) ALOX15RECQLTSHRTAS2R38BCAT1
SCHEMBL563340 1.00 ALOX15 (0.33) ALOX15RECQLTSHRTAS2R38BCAT1
SCHEMBL14556333 1.00 ALOX15 (0.33) ALOX15RECQLTSHRTAS2R38BCAT1
Hydrochloric Acid SCHEMBL3065209 0.96 ALOX15 (0.32) ALOX15RECQLTSHRTAS2R38
Hydrochloric Acid SCHEMBL3597570 0.96 ALOX15 (0.32) ALOX15RECQLTSHRTAS2R38
Hydrochloric Acid SCHEMBL2659325 0.96 ALOX15 (0.32) ALOX15RECQLTSHRTAS2R38
SCHEMBL19773677 0.86
SCHEMBL13866900 0.83
Hydrochloric Acid SCHEMBL9487889 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702017-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2026-03-04 EP disclosed
EP-4695231-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2026-02-18 EP disclosed
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
EP-4192831-B1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO INC (US) 2025-10-22 EP disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed
WO-2025034613-A1 3H-IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AS NON-COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-02-13 WO disclosed
US-20250034122-A1 SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS MISSION THERAPEUTICS LIMITED (GB) 2025-01-30 US disclosed
WO-2024216209-A1 COMPOUNDS, COMPOSITIONS, AND METHODS NICO THERAPEUTICS, INC. (US) 2024-10-17 WO disclosed
EP-4441044-A1 SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS Mission Therapeutics Limited (GB) 2024-10-09 EP disclosed
US-20020052395-A1 Diphenyl ether compounds useful in therapy ANDREWS MARK DAVID (GB) 2002-05-02 US disclosed
WO-2001062726-A2 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB, S.A. (BE) 2001-08-30 WO disclosed
US-6228847-B1 ADMINISTERING PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES AS PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR ALBERT EINSTEIN COLLEGE OF MEDICINE 2001-05-08 US disclosed
EP-1023308-A1 INHIBITORS OF NUCLEOSIDE METABOLISM ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2000-08-02 EP disclosed
US-6066722-A Inhibitors of nucleoside metabolism ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2000-05-23 US disclosed
US-5985848-A EFFECTIVE INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE AND/OR NUCLEOSIDE HYDROLASES; TREATMENT AND/OR PROPHYLAXIS OF A PROTOZOAN INFECTION ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1999-11-16 US disclosed
WO-1999019338-A1 INHIBITORS OF NUCLEOSIDE METABOLISM ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1999-04-22 WO disclosed
EP-0056577-B1 TRIAZOLYL-COUMARIN DERIVATIVES, THEIR PREPARATION AND USE AS OPTICAL BRIGHTENING AGENTS SCINTILLATORS AND DYESTUFFS FOR LASERS BAYER AG (DE) 1984-12-19 EP disclosed
US-4426530-A Triazolylcoumarin compounds, and their preparation and use as optical brighteners, scintillators and laser dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1984-01-17 US disclosed
EP-0056577-A1 Triazolyl-coumarin derivatives, their preparation and use as optical brightening agents scintillators and dyestuffs for lasers BAYER AG (DE) 1982-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALOX15 2581/4885RECQL 910/4885TSHR 3881/4885
US-20250034122-A1 SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS USP30, USP47, USP1 ALOX15 4202/4885RECQL 1473/4885TSHR 4463/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 ALOX15 2760/4885RECQL 3600/4885TSHR 1159/4885
US-20020052395-A1 Diphenyl ether compounds useful in therapy CBR1, OGFR, CBR3 ALOX15 3629/4885RECQL 1380/4885TSHR 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.