SCHEMBL51406

SCHEMBL51406

O=S(=O)(c1ccc(O)cc1)c1ccc(OCc2cccc(COc3ccc(S(=O)(=O)c4ccc(O)cc4)cc3)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
CYP1A2 P05177 1/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56
CYP2C19 P33261 1/20 0.56
PTGS2 P35354 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HIF1A Q16665 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
GAA P10253 1/20 0.53
PKM P14618 1/20 0.53
PTPN1 P18031 2/20 0.53
PTPRC P08575 1/20 0.53
FFAR1 O14842 4/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA4 P22748 1/20 0.51
CA5A P35218 1/20 0.51
CA7 P43166 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419372 0.90 MAOB (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL419556 0.89 LMNA (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6280745 0.86 GAA (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL51564 0.86 GAA (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8982841 0.86 CYP1A2 (0.45) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5633862 0.86 LMNA (0.73) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11009256 0.84 LMNA (0.67) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1791486 0.84 CA12 (0.52) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27655068 0.82 MRGPRX4 (0.70) PKM
SCHEMBL7108878 0.81 CA12 (0.74) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7149713-A None JP disclosed
EP-3475095-B1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH CO LTD (JP) 2020-01-22 EP disclosed
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH COMPANY, LTD. (JP) 2019-05-23 US disclosed
EP-3475095-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2019-05-01 EP disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
US-8563468-B2 Color developing composition containing molecular compound, and recording material NIPPON SODA CO., LTD. (JP) 2013-10-22 US disclosed
US-8497227-B2 Diphenylsulfone bridged compound, color forming substance for thermal recording and thermal recording material NICCA CHEMICAL CO., LTD. (JP) 2013-07-30 US disclosed
EP-2332733-B1 COLOR DEVELOPING COMPOSITION CONTAINING MOLECULAR COMPOUND, AND RECORDING MATERIAL NIPPON SODA CO (JP) 2012-11-28 EP disclosed
US-8283286-B2 Thermosensitive recording material NICCA CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
US-6677275-B1 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-01-13 US disclosed
US-20030186810-A1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD. 2003-10-02 US disclosed
EP-0999072-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2003-05-02 EP disclosed
EP-1273570-A1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO., LTD. (JP) 2003-01-08 EP disclosed
US-6303540-B1 CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-10-16 US disclosed
EP-1092552-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-1092553-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-0999072-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-10 EP disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed
JP-H07149713-A SULFONYL COMPOUND, ITS PRODUCTION AND HEAT-SENSITIVE RECORDING MATERIAL USING THE SAME SANKO CHEM CO LTD 1995-06-13 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE CACNA1S, NCS1, TRPA1 LMNA 2730/4885CYP1A2 609/4885PTGS1 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.