Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928924 | 1.00 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL8043209 | 0.83 | TRPA1 (0.32) | — | |
| SCHEMBL2803312 | 0.82 | L3MBTL1 (0.40) | — | |
| SCHEMBL2803314 | 0.82 | L3MBTL1 (0.40) | — | |
| SCHEMBL7838338 | 0.80 | — | — | |
| SCHEMBL8048676 | 0.76 | NPC1 (0.50) | NPSR1 | |
| SCHEMBL13928900 | 0.76 | LMNA (0.39) | — | |
| SCHEMBL13928915 | 0.74 | MAPT (0.33) | — | |
| SCHEMBL8043508 | 0.73 | LMNA (0.41) | NPSR1 | |
| SCHEMBL13929157 | 0.72 | APP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213341-A1 | Spiroindolinone derivatives | CHEN LI | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213341-A1 | Spiroindolinone derivatives | MKI67, PKD1, RCC2 | NPSR1 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.