SCHEMBL5635203

SCHEMBL5635203

Cc1cc(-c2ccc(Cl)cc2)c(O)c(C(C)(C)C)c1.c1c[nH]nn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
CA2 P00918 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
TYR P14679 1/20 0.40
HSPA5 P11021 1/20 0.35
CYP2C9 P11712 5/20 0.34
CYP2C19 P33261 5/20 0.34
HIF1A Q16665 3/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPT P10636 3/20 0.32
TRPV1 Q8NER1 1/20 0.32
CYP2D6 P10635 2/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27408525 0.88 HSP90AA1 (0.40) CA2CYP2C9CYP2C19MGAMGAA
SCHEMBL3672236 0.84 CA2 (0.55) SMN1; SMN2CA2ALDH1A1POLBTYR
Bumetrizole SCHEMBL13835785 0.76 NPC1 (0.44) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL4366547 0.70 HSP90AA1 (0.49) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL31027271 0.70 CA2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL17500171 0.70 CA2 (0.59) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL808957 0.69 SMN1; SMN2 (0.40) SMN1; SMN2CA2ALDH1A1POLBTYR
Parachlorophenol SCHEMBL717321 0.68 MAPK1 (0.41) SMN1; SMN2ALDH1A1GAAMAPTHSD17B10
SCHEMBL8669592 0.68 AMY1A (0.49) SMN1; SMN2CA2ALDH1A1POLBTYR
SCHEMBL30782815 0.67 SMN1; SMN2 (0.77) SMN1; SMN2CA2ALDH1A1POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102650828-A Colored photosensitive resin composition, color filter and LCD (Liquid Crystal Display) device BOE TECHNOLOGY GROUP CO LTD 2012-08-29 CN disclosed
US-20070003735-A1 Display device FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 US disclosed