SCHEMBL8669592

SCHEMBL8669592

Cc1cc(-c2nc3cc(Cl)ccc3[nH]2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 10/20 0.49
ALDH1A1 P00352 1/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
F2 P00734 1/20 0.40
F10 P00742 1/20 0.40
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
PLAT P00750 1/20 0.40
PRSS1 P07477 1/20 0.40
NPBWR1 P48145 1/20 0.37
SSTR2 P30874 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13379418 0.78 AMY1A (0.57) AMY1AALDH1A1
SCHEMBL11250595 0.78 AMY1A (0.68) AMY1AF2F10PLGPLAU
SCHEMBL28991902 0.78 F2 (0.54) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL29422000 0.78 F2 (0.54) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL13406025 0.75 ALDH1A1 (0.58) AMY1AALDH1A1SMN1; SMN2NPBWR1
SCHEMBL2354486 0.73 MGAM (0.51) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL7388739 0.73 AMY1A (0.53) AMY1AALDH1A1SMN1; SMN2F2F10
SCHEMBL13379426 0.72 AMY1A (0.51) AMY1A
SCHEMBL1171146 0.72 ALDH1A1 (0.53) AMY1AALDH1A1SMN1; SMN2
SCHEMBL3672236 0.71 CA2 (0.55) ALDH1A1CA2POLBTYRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5707690-A CLEAR COAT WITH ULTRAVIOLET RADIATION ABSORBER, HYDROXYBENZOPHENONE DERIVATIVES CIBA-GEIGY CORPORATION (US) 1998-01-13 US disclosed
EP-0445076-B1 Stable dispersions of benzotriazole ultra-violet absorbing agents CIBA GEIGY AG (CH) 1995-08-09 EP disclosed