⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442929 | 0.92 | — | — | |
| SCHEMBL374773 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL7382880 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL6539108 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL970516 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL3980051 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL1654498 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL3972155 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL1401237 | 0.89 | TSHR (0.63) | — | |
| SCHEMBL1702085 | 0.89 | TSHR (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230102146-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | SHENZHEN NEPTUNUS PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2023-03-30 | — | — | US | claimed |
| EP-4108666-A1 | MULTI-TARGET TYROSINE KINASE INHIBITOR | Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd. (CN) | 2022-12-28 | — | — | EP | claimed |
| CN-113336768-B | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-113336768-A | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-108689903-B | Novel preparation method of brivaracetam | 北京艾百诺医药股份有限公司 | 2019-12-24 | — | — | CN | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| EP-2507210-A1 | CYCLOHEXANE DERIVATIVES AS INHIBITORS OF ACETYL-COA CARBOXYLASE (ACC) | Novartis AG (CH) | 2012-10-10 | — | — | EP | claimed |
| EP-1841747-B1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2012-09-05 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-8034958-B2 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UOB Pharma, S.A. (BE) | 2011-10-11 | — | — | US | claimed |
| WO-1999007734-A2 | HEPATITIS C INHIBITOR PEPTIDE ANALOGUES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1999-02-18 | — | — | WO | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| WO-1998049197-A1 | OLIGOPEPTIDIC INHIBITORS OF ELASTASES AND METHODS OF PREPARATION THEREOF | VÚFB, A.S. (CZ) | 1998-11-05 | — | — | WO | claimed |
| US-5811389-A | INHIBITING PLATELET AGGREGATION; BLOOD DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | claimed |
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | claimed |
| EP-0333174-B1 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0592791-A2 | Tricyclic compounds and peptide derivatives thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1994-04-20 | — | — | EP | claimed |
| US-5187156-A | D-Tryptophan- and Phenylalanine-containing tripeptides as tachykinin antagonists; asthma | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| EP-0333174-A2 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-20 | — | — | EP | claimed |
| US-4659734-A | BACTERICIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1987-04-21 | — | — | US | claimed |