Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109225 | 0.89 | KMT2A (0.42) | BCHETSHRTDP1L3MBTL1KMT2A | |
| SCHEMBL2117227 | 0.89 | KMT2A (0.42) | BCHETSHRTDP1L3MBTL1KMT2A | |
| SCHEMBL5635573 | 0.79 | NOTUM (0.53) | BCHETSHRTDP1L3MBTL1KMT2A | |
| SCHEMBL7165911 | 0.78 | NPC1 (0.45) | TDP1L3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL18714661 | 0.78 | BCHE (0.45) | BCHETSHRTDP1L3MBTL1ESR1 | |
| SCHEMBL30109124 | 0.78 | NOTUM (0.39) | BCHETSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL4167876 | 0.78 | NOTUM (0.39) | BCHETSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL2117213 | 0.76 | CA12 (0.49) | BCHEKMT2AMAPK1CNR2TP53 | |
| SCHEMBL31549612 | 0.75 | ESR1 (0.49) | BCHETSHRTDP1L3MBTL1ESR1 | |
| SCHEMBL30711258 | 0.74 | ACLY (0.47) | BCHEL3MBTL1KMT2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | US | disclosed |
| EP-1689710-A1 | INDOLE DERIVATIVES FOR USE AS CHEMICAL UNCOUPLER | NOVO NORDISK A/S (DK) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051908-A1 | INDOLE DERIVATIVES FOR USE AS CHEMICAL UNCOUPLER | NOVO NORDISK A/S (DK) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | GPR119, IDO2, IDO1 | BCHE 2543/4885OXER1 470/4885TSHR 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.