Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAT2A | P31153 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.30 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287646 | 0.76 | NOTUM (0.52) | MAPTMAT2AADORA2ANOTUMACLY | |
| SCHEMBL5636397 | 0.74 | MAPT (0.39) | MAPTMEN1KMT2AHPGDNPSR1 | |
| SCHEMBL9672458 | 0.70 | NOTUM (0.44) | MAPTMAT2AADORA2ANOTUMF2RL1 | |
| SCHEMBL11370837 | 0.66 | MAPT (0.41) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11370833 | 0.64 | MAPT (0.39) | MAPT | |
| SCHEMBL17144712 | 0.64 | NOTUM (0.48) | MAPTMAT2AADORA2ANOTUMACLY | |
| SCHEMBL8170428 | 0.62 | MAPT (0.39) | MAPTMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL18787661 | 0.61 | ADORA2A (0.36) | MAPTMAT2AADORA2ANOTUMMEN1 | |
| SCHEMBL10383600 | 0.61 | ALDH1A1 (0.47) | MAPTNOTUMMEN1KMT2AKDM4E | |
| SCHEMBL6119863 | 0.61 | NOTUM (0.53) | MAPTADORA2ANOTUMF2RL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176321-B2 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | FUJIFILM CORPORATION (JP) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204589-A1 | Method for producing 3-amino-4-substituted-5-pyrazolones | KCNH3, KCNH2, KCNJ11 | MAPT 4832/4885MAT2A 2467/4885ADORA2A 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.