SCHEMBL5638

SCHEMBL5638

OCCc1ccc(Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.59
TAAR1 Q96RJ0 3/20 0.56
HTR2A P28223 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TSHR P16473 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ALOX5 P09917 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
BACE1 P56817 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL7110052 0.93 CA2 (0.52) CA2TAAR1HTR2ATDP1CA12
SCHEMBL10791150 0.93 CA2 (0.52) CA2TAAR1HTR2ATDP1CA12
SCHEMBL11128251 0.89 CA2 (0.48) CA2TAAR1HTR2ATDP1CA12
SCHEMBL40656 0.85 CA2 (0.77) CA2TAAR1TDP1CA12CA1
SCHEMBL5515 0.84 TAAR1 (0.52) CA2TAAR1HTR2ACYP4F2CYP4A11
SCHEMBL3665177 0.83 CA2 (0.43) CA2TAAR1HTR2ATDP1TSHR
SCHEMBL1624419 0.82 CA2 (0.52) CA2TAAR1HTR2ACYP4F2CYP4A11
SCHEMBL626076 0.82 TAAR1 (0.68) TAAR1HTR2AALDH1A1CYP2A6POLB
SCHEMBL6057959 0.82 CA2 (0.72) CA2TDP1CA12CA1CA4
SCHEMBL1044964 0.80 CA2 (0.53) CA2TAAR1HTR2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004802-A Method for synthesizing N-alkyl substituted 3, 5-dimethylpyrazole compound by one-pot method 四川轻化工大学 2025-05-16 CN claimed
CN-119409729-A Method for preparing S- (1H-pyrrole-2-yl) substituted phosphorothioate compound 岳阳凯茂化工材料有限公司 2025-02-11 CN claimed
CN-113845442-B Method for preparing p-bromobenzonitrile 孙国伟 2023-09-29 CN claimed
CN-114874121-A Method for preparing material containing monothiocarbonate group and product 浙江大学 2022-08-09 CN claimed
CN-110776422-B Method for preparing ester by irradiating halogenated aromatic hydrocarbon, alcohol and carbonyl source by ultraviolet light 福州大学 2021-07-27 CN claimed
CN-112239541-A Dielectric elastomer material with high dielectric constant, low modulus and high breakdown field strength and preparation method thereof 北京化工大学 2021-01-19 CN claimed
CN-110776422-A Method for preparing ester by irradiating halogenated aromatic hydrocarbon, alcohol and carbonyl source by ultraviolet light 福州大学 2020-02-11 CN claimed
CN-104961665-B Cool compound of six benzos of dovetail shaped side chain Sulfide-containing Hindered and preparation method thereof 北京印刷学院 2017-03-01 CN claimed
CN-104961665-A Hexabenzocoronene compound containing thioether in dovetail-like side-chain and preparation method thereof BEIJING INST GRAPHIC COMM 2015-10-07 CN claimed
CN-102584655-B Coronene compound containing thioether in lateral chain and preparation method thereof BEIJING INST GRAPHIC COMM 2014-06-25 CN claimed
CN-102584655-A Coronene compound containing thioether in lateral chain and preparation method thereof BEIJING INST GRAPHIC COMM 2012-07-18 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-4255340-A Method for preparing an alkenyl-substituted dicarboxylic acid anhydride TEXACO INC. (US) 1981-03-10 US claimed
CN-122059780-A Asymmetric synthesis method of alpha-chiral ester compound 内蒙古大学 2026-05-19 CN disclosed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
EP-4166557-B1 INTERMEDIATES OF N-(3-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES NOVARTIS AG (CH) 2026-05-06 EP disclosed
US-4304911-A ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS STERLING DRUG INC. (US) 1981-12-08 US disclosed
US-4281065-A Phencyclidine conjugates to antigenic proteins and enzymes SYVA COMPANY (US) 1981-07-28 US disclosed
US-4255340-A Method for preparing an alkenyl-substituted dicarboxylic acid anhydride TEXACO INC. (US) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624044-B2 SMARCA degraders and uses thereof SMARCA1, SMARCC1, SMARCA2 CA2 2413/4885TAAR1 3399/4885HTR2A 3542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.