SCHEMBL5515

SCHEMBL5515

OCCCc1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.52
HTR2A P28223 1/20 0.52
CA2 P00918 4/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
CYP4A11 Q02928 2/20 0.47
LTA4H P09960 1/20 0.46
EPHX2 P34913 1/20 0.46
SIGMAR1 Q99720 1/20 0.43
PPARA Q07869 1/20 0.42
HMOX1 P09601 1/20 0.42
CYP4F2 P78329 1/20 0.41
PLAAT3 P53816 1/20 0.41
PLAAT5 Q96KN8 1/20 0.41
PLAAT2 Q9NWW9 1/20 0.41
PLAAT4 Q9UL19 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1624419 0.93 CA2 (0.52) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL1044964 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL15352178 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL5310822 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL1046537 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL16414630 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL16467630 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL16414852 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL2382177 0.91 CA2 (0.53) TAAR1HTR2ACA2CYP11B1CYP11B2
SCHEMBL239040 0.87 CA2 (0.60) CA2CYP4A11LTA4HEPHX2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574033-A Phenylalanine derivative containing alkynyl and benzophenone groups and synthesis method 中国人民解放军军事科学院防化研究院 2023-08-11 CN claimed
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF GENOSCO INC (US) 2026-04-23 US disclosed
US-12503452-B2 Antimicrobial compounds and methods CURZA GLOBAL, LLC (US) 2025-12-23 US disclosed
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
US-20240390387-A1 SULFONAMIDE OR SULFINAMIDE COMPOUND HAVING EFFECT OF INDUCING BRD4 PROTEIN DEGRADATION AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2024-11-28 US disclosed
CN-115074138-B Liquid crystal composition and liquid crystal display device 达兴材料股份有限公司 2024-11-19 CN disclosed
CN-118955244-A Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex 延安大学 2024-11-15 CN disclosed
US-12102641-B2 Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2024-10-01 US disclosed
CN-118598898-A Synthetic method of non-natural alpha-amino acid derivative 华中科技大学 2024-09-06 CN disclosed
WO-1996004267-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1996-02-15 WO disclosed
EP-0328643-B1 (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION TERUMO CORP (JP) 1994-07-06 EP disclosed
US-5145865-A Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1992-09-08 US disclosed
EP-0496342-A1 New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient Nippon Kayaku Kabushiki Kaisha (JP) 1992-07-29 EP disclosed
US-5043142-A Measuring peroxide-active substances TERUMO KABUSHIKI KAISHA (JP) 1991-08-27 US disclosed
US-4990505-A Treating asthma, bronchitis; adrenergic stimulants GLAXO GROUP LIMITED (GB) 1991-02-05 US disclosed
EP-0162208-B1 NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) 1989-11-23 EP disclosed
EP-0328643-A1 (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION TERUMO KABUSHIKI KAISHA (JP) 1989-08-23 EP disclosed
EP-0296802-A1 Aminocyclopentyl ethers and their preparation and pharmaceutical formulation GLAXO GROUP LIMITED (GB) 1988-12-28 EP disclosed
US-4683234-A HYPOTENSIVE AGENTS, ANTI-ANGINA SUNTORY LIMITED (JP) 1987-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF CRBN, PSMB3, PSMB1 TAAR1 2939/4885HTR2A 2559/4885CA2 2852/4885
US-12102641-B2 Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof BRD4, BRD1, BRD2 TAAR1 3704/4885HTR2A 3430/4885CA2 4278/4885
US-20240390387-A1 SULFONAMIDE OR SULFINAMIDE COMPOUND HAVING EFFECT OF INDUCING BRD4 PROTEIN DEGRADATION AND PHARMACEUTICAL USE THEREOF BRD4, BRD1, BRD2 TAAR1 3704/4885HTR2A 3430/4885CA2 4278/4885
US-12503452-B2 Antimicrobial compounds and methods MPO, NISCH, RPN2 TAAR1 4825/4885HTR2A 4712/4885CA2 2151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.