Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995475 | 0.90 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL5639703 | 0.83 | HTT (0.37) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL5640101 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL5641551 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MAPTRAB9ANPC1NR1I2 | |
| SCHEMBL6380186 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL5640472 | 0.77 | GAA (0.41) | MAPTKDM4EPOLB | |
| SCHEMBL7831898 | 0.67 | RAB9A (0.46) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL701678 | 0.66 | — | — | |
| SCHEMBL29603808 | 0.66 | — | — | |
| SCHEMBL701014 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301034-B2 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-27 | — | — | US | claimed |
| EP-1301469-B1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AG (DE) | 2006-06-21 | — | — | EP | claimed |
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-07 | — | — | US | claimed |
| US-7301034-B2 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-27 | — | — | US | disclosed |
| EP-1301469-B1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | CBR1, CBR3, AOC3 | ALDH1A1 326/4885MAPT 4763/4885RAB9A 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.