⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666084 | 0.84 | — | — | |
| SCHEMBL6982486 | 0.84 | — | — | |
| SCHEMBL5637534 | 0.82 | TUBB4A (0.32) | — | |
| SCHEMBL5638953 | 0.79 | — | — | |
| SCHEMBL30480757 | 0.76 | ALOX15 (0.31) | — | |
| SCHEMBL701268 | 0.74 | EDNRB (0.30) | — | |
| SCHEMBL6995825 | 0.74 | — | — | |
| SCHEMBL6993796 | 0.74 | — | — | |
| SCHEMBL700999 | 0.73 | — | — | |
| Bromide SCHEMBL28689439 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118788251-B | Method for preparing 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydroisoxazole | 苏州开元民生科技股份有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-118788251-A | Method for preparing 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydroisoxazole | 苏州开元民生科技股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-113402511-B | Preparation method of topramezone | 西安交通大学 | 2023-04-07 | — | — | CN | claimed |
| CN-113402511-A | Preparation method of topramezone | 西安交通大学 | 2021-09-17 | — | — | CN | claimed |
| JP-4818511-B2 | — | — | 2011-11-16 | — | — | JP | claimed |
| US-7301034-B2 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-27 | — | — | US | claimed |
| EP-1301469-B1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AG (DE) | 2006-06-21 | — | — | EP | claimed |
| EP-1131307-B1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AG (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20030229232-A1 | Herbicides | RACK MICHAEL (DE) | 2003-12-11 | — | — | US | claimed |
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-07 | — | — | US | claimed |
| EP-1301469-A1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-16 | — | — | EP | claimed |
| US-6548677-B1 | Halogenating o-xylene; reacting with hydrogen peroxide and halogenating agent to form a benzyl halide; oxidation to aldehyde; oximination, cyclization, and sulfiding | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | claimed |
| US-20020156290-A1 | Herbicides | RACK MICHAEL (DE) | 2002-10-24 | — | — | US | claimed |
| WO-2002006211-A1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-24 | — | — | WO | claimed |
| EP-1131307-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029395-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | claimed |
| CN-118788251-B | Method for preparing 3- [ 3-bromo-2-methyl-6- (methylsulfonyl) phenyl ] -4, 5-dihydroisoxazole | 苏州开元民生科技股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119371413-A | Topramezone and its preparation method Process for the preparation of ketones | 安徽丰乐农化有限责任公司 | 2025-01-28 | — | — | CN | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| WO-2002006211-A1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-24 | — | — | WO | disclosed |