Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581343 | 0.84 | MAPT (0.68) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL885028 | 0.84 | MAPT (0.68) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| Isopeonol SCHEMBL29757918 | 0.84 | MAOB (0.57) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| Isopeonol SCHEMBL3713802 | 0.84 | MAOB (0.57) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL536099 | 0.84 | CA12 (0.55) | ALDH1A1HPGDSIRT1MAPTHSD17B10 | |
| Isopeonol SCHEMBL1376231 | 0.84 | MAOB (0.57) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL31009365 | 0.82 | CA12 (0.67) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL12509335 | 0.82 | SIRT1 (0.51) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL7619139 | 0.82 | CA12 (0.67) | ALDH1A1HPGDCYP3A4MAPK1HTT | |
| SCHEMBL9021036 | 0.82 | SIRT1 (0.51) | ALDH1A1HPGDCYP3A4MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105753-B | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114105753-A | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2022-03-01 | — | — | CN | disclosed |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-8436036-B2 | Diaryl ethers | JANSSEN R&D IRELAND (IE) | 2013-05-07 | — | — | US | disclosed |
| EP-2421855-A1 | DIARYL ETHERS | Tibotec Pharmaceuticals (IE) | 2012-02-29 | — | — | EP | disclosed |
| US-20120034678-A1 | Diaryl Ethers | JANSSEN SCIENCES IRELAND UC (IE) | 2012-02-09 | — | — | US | disclosed |
| WO-2010122162-A1 | DIARYL ETHERS | TIBOTEC PHARMACEUTICALS (IE) | 2010-10-28 | — | — | WO | disclosed |
| US-5061798-A | Intermediates in the formation of synthetic hormones, mimic effects of thyroid hormones; little or no effect on the heart | SMITH KLINE & FRENCH LABORATORIES, LTD. (GB) | 1991-10-29 | — | — | US | disclosed |
| EP-0188351-B1 | CHEMICAL COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| US-4910305-A | Containing a protected 4-hydroxyphenyl | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-03-20 | — | — | US | disclosed |
| US-4826876-A | WITHOUT EFFECT ON HEART | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-05-02 | — | — | US | disclosed |
| US-4766121-A | NOT AFFECTING THE HEART | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1988-08-23 | — | — | US | disclosed |
| EP-0188351-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034678-A1 | Diaryl Ethers | SLC10A1, CYP2F1, UGT1A1 | ALDH1A1 325/4885HPGD 1628/4885CYP3A4 58/4885 |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | KDM1B, KDM2A, KDM1A | ALDH1A1 1174/4885HPGD 1383/4885CYP3A4 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.