Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HAAO | P46952 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138242 | 0.85 | ALDH1A1 (0.42) | ALOX15ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL30595097 | 0.85 | ALDH1A1 (0.42) | ALOX15ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL5638807 | 0.84 | L3MBTL1 (0.38) | ALDH1A1LMNAL3MBTL1BCAT2 | |
| SCHEMBL1495431 | 0.83 | ALDH1A1 (0.41) | ALOX15ALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL1358700 | 0.81 | ALDH1A1 (0.40) | ALOX15ALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL27316603 | 0.81 | ALDH1A1 (0.40) | ALOX15ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL1495458 | 0.80 | LMNA (0.53) | ALOX15ALDH1A1LMNAMAPK1CYP1A2 | |
| SCHEMBL1780016 | 0.80 | L3MBTL1 (0.42) | ALOX15ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL7939680 | 0.80 | ALDH1A1 (0.39) | ALOX15ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL3764955 | 0.80 | LMNA (0.45) | ALOX15ALDH1A1LMNAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196229-B2 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-27 | — | — | US | disclosed |
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235793-A1 | Benzoylcyclohexenone derivatives | CYC1, CYP1B1, CYP1A1 | ALOX15 2862/4885ALDH1A1 389/4885LMNA 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.