Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421486 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL15453339 | 0.84 | PTAFR (0.42) | ALDH1A1HSD17B10KDM4EPTAFRMEN1 | |
| SCHEMBL6480845 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL1092120 | 0.81 | PTAFR (0.39) | ALDH1A1HSD17B10KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23421487 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL31264295 | 0.79 | ALDH1A1 (0.79) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL21766542 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL23420928 | 0.77 | CYP3A4 (0.37) | ALDH1A1HSD17B10KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28310672 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL6570759 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HSD17B10L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241721-B2 | carboxamide derivatives as active ingredients which have microbiocidal activity, in particular fungicidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060100250-A1 | Biphenyl derivatives and their use as fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100250-A1 | Biphenyl derivatives and their use as fungicides | CBR3, CYP8B1, PYM1 | ALDH1A1 2096/4885HSD17B10 292/4885L3MBTL1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.