Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 7/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 4/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.32 |
| ▸ | LCK | P06239 | 3/20 | 0.32 |
| ▸ | PRKACA | P17612 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.32 |
| ▸ | LTK | P29376 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421487 | 0.94 | ALDH1A1 (0.43) | PTAFRKDRALDH1A1HSD17B10CSF1R | |
| SCHEMBL15453339 | 0.81 | PTAFR (0.42) | PTAFRALDH1A1HSD17B10NR1H2NR1H3 | |
| SCHEMBL5640059 | 0.81 | ALDH1A1 (0.58) | PTAFRALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL23421486 | 0.78 | ALDH1A1 (0.50) | PTAFRALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL5319523 | 0.76 | NOS2 (0.44) | PTAFRKDRAURKBAURKACDK2 | |
| SCHEMBL6318211 | 0.75 | NPC1 (0.44) | KDRFLT3KITALDH1A1HSD17B10 | |
| SCHEMBL23420928 | 0.74 | CYP3A4 (0.37) | PTAFRALDH1A1HSD17B10NR1H2NR1H3 | |
| SCHEMBL3481745 | 0.74 | NR1H2 (0.38) | PTAFRNR1H2NR1H3SCN5AACHE | |
| SCHEMBL1599696 | 0.74 | CNR2 (0.43) | AURKBMAP4K4MAPK8CDK5CLK4 | |
| SCHEMBL13062850 | 0.74 | ENPP1 (0.57) | ALDH1A1HSD17B10ENPP3ENPP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | claimed |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-12-14 | — | — | US | claimed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | disclosed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | disclosed |
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | DDT, AHR, DDC | PTAFR 1702/4885KDR 2193/4885FLT3 128/4885 |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | DDT, AHR, DDC | PTAFR 1702/4885KDR 2193/4885FLT3 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.