Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465087 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7930838 | 0.79 | ALDH1A1 (0.43) | METAP2ALDH1A1POLBKDM4EUSP2 | |
| SCHEMBL3963370 | 0.78 | PPARA (0.78) | PPARAPPARGMCL1ALDH1A1NPC1 | |
| SCHEMBL903987 | 0.76 | KDM4E (0.45) | ALDH1A1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16737197 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EUSP2HPGDCYP2C19 | |
| SCHEMBL25421342 | 0.76 | PPARA (0.65) | PPARAPPARGMCL1ALDH1A1NPC1 | |
| SCHEMBL25421082 | 0.76 | PPARA (0.57) | PPARAPPARGMETAP2MCL1ALDH1A1 | |
| SCHEMBL25421010 | 0.75 | PPARA (0.53) | PPARAPPARGMETAP2MCL1ALDH1A1 | |
| SCHEMBL3181925 | 0.75 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4EUSP2HPGD | |
| SCHEMBL10674685 | 0.75 | PPARA (0.71) | PPARAPPARGALDH1A1KAT8RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205313-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2007-04-17 | — | — | US | disclosed |