Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839257 | 0.89 | HSD11B1 (0.46) | ALDH1A1KDM4EUSP2HPGDCYP2C19 | |
| SCHEMBL7922665 | 0.88 | CSNK2A1 (0.46) | ALDH1A1KDM4EUSP2HPGDCYP2C19 | |
| SCHEMBL6643810 | 0.87 | HSP90AA1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CA1 | |
| SCHEMBL3303470 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EUSP2HPGDCYP2C19 | |
| SCHEMBL14872770 | 0.82 | CA1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10CSNK2A1 | |
| SCHEMBL8154524 | 0.82 | CSNK2A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CSNK2A1 | |
| SCHEMBL903987 | 0.82 | KDM4E (0.45) | ALDH1A1KDM4EHSD11B1MEN1KMT2A | |
| SCHEMBL16737197 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4EUSP2HPGDCYP2C19 | |
| SCHEMBL6942043 | 0.80 | CA1 (0.44) | ALDH1A1KDM4EUSP2CA1CA2 | |
| SCHEMBL3493018 | 0.80 | HSD11B1 (0.46) | ALDH1A1CYP2C19CSNK2A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |