SCHEMBL564325

SCHEMBL564325

C=C(C)C(CC=C(C)C)Cc1c(O)c(CC=C(C)C)c(O)c2c1OC(c1ccc(O)cc1O)CC2=O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 0.80
ABCG2 Q9UNQ0 3/20 0.80
CACNA1H O95180 3/20 0.80
SLC5A1 P13866 2/20 0.80
SLC5A2 P31639 2/20 0.80
CACNA1G O43497 2/20 0.80
IDO1 P14902 2/20 0.77
ESR1 P03372 3/20 0.73
PTGS1 P23219 1/20 0.73
SOAT1 P35610 1/20 0.73
BCHE P06276 1/20 0.73
ACHE P22303 1/20 0.73
MEN1 O00255 1/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 1/20 0.58
XBP1 P17861 1/20 0.58
KMT2A Q03164 1/20 0.58
CYP19A1 P11511 1/20 0.57
MAOA P21397 2/20 0.53
MAOB P27338 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27013439 1.00 BACE1 (0.80) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL29929166 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL17626648 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL29929533 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL29776828 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL10307524 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL15090973 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL904617 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
Sophoraflavanone G SCHEMBL2228023 0.89 BACE1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2
SCHEMBL17626616 0.88 IDO1 (1.00) BACE1ABCG2CACNA1HSLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377486-B2 Cosmetic composition containing an adenium obesum extract, use thereof and method for cosmetic care including the use thereof LVMH RECHERCHE (FR) 2013-02-19 US claimed
US-20100272662-A1 COSMETIC COMPOSITION CONTAINING AN ADENIUM OBESUM EXTRACT, USE THEREOF AND METHOD FOR COSMETIC CARE INCLUDING THE USE THEREOF LVMH RECHERCHE (FR) 2010-10-28 US claimed
WO-2008152268-A2 COSMETIC COMPOSITION CONTAINING AN ADENIUM OBESUM EXTRACT, USE THEREOF AND METHOD FOR COSMETIC CARE INCLUDING THE USE THEREOF LVMH RECHERCHE (FR) 2008-12-18 WO claimed
CN-1348762-A Application of kusheng (sophora Flavescences) flavone in preparing hypoglycemic LUZHOU BAOGUANG PHARMACEUTICAL (CN) 2002-05-15 CN claimed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 US disclosed
US-10744219-B2 Air freshener composition and preparation method thereof Guorun Biotechnology (Shenzhen) Co., Ltd. (CN) 2020-08-18 US disclosed
US-20200164096-A1 AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREOF Guorun Biotechnology (Shenzhen) Co., Ltd. (CN) 2020-05-28 US disclosed
EP-3388137-B1 AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREFOR WANG JINGNING (CN) 2020-04-15 EP disclosed
EP-3388137-A1 AIR FRESHENER COMPOSITION AND PREPARATION METHOD THEREFOR Wang, Jingning (CN) 2018-10-17 EP disclosed
US-8414933-B2 Brassocattleya marcella koss orchid extract and use thereof as skin depigmentation agent L V M H RECHERCHE (FR) 2013-04-09 US disclosed
US-8377486-B2 Cosmetic composition containing an adenium obesum extract, use thereof and method for cosmetic care including the use thereof LVMH RECHERCHE (FR) 2013-02-19 US disclosed
CN-102908341-A Vitexicarpin used as pharmaceutical active ingredient with anti-angiogenesis function UNIV TSINGHUA 2013-02-06 CN disclosed
WO-2010066150-A9 GENE NETWORK-BASED METHOD FOR CONFIRMING DRUG ACTION 清华大学 (CN) 2011-07-21 WO disclosed
CN-102030812-A Timosaponin A-III serving as medicinal active ingredient with angiogenesis resistance UNIV TSINGHUA 2011-04-27 CN disclosed
CN-102028679-A Vitexin as active ingredient of medicine with anti-angiogenesis effect UNIV TSINGHUA 2011-04-27 CN disclosed
US-20100272662-A1 COSMETIC COMPOSITION CONTAINING AN ADENIUM OBESUM EXTRACT, USE THEREOF AND METHOD FOR COSMETIC CARE INCLUDING THE USE THEREOF LVMH RECHERCHE (FR) 2010-10-28 US disclosed
US-20090258093-A1 Use of a brassocattleya marcella koss orchid extract as an active agent to prevent or delay the appearance of signs of cutaneous aging L.V.M.H. RECHERCHE 2009-10-15 US disclosed
US-20090232758-A1 Brassocattleya marcella koss orchid extract and use thereof as skin depigmentation agent L V M H RECHERCHE 2009-09-17 US disclosed
WO-2008152268-A2 COSMETIC COMPOSITION CONTAINING AN ADENIUM OBESUM EXTRACT, USE THEREOF AND METHOD FOR COSMETIC CARE INCLUDING THE USE THEREOF LVMH RECHERCHE (FR) 2008-12-18 WO disclosed
CN-1348762-A Application of kusheng (sophora Flavescences) flavone in preparing hypoglycemic LUZHOU BAOGUANG PHARMACEUTICAL (CN) 2002-05-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS THPO, SERPINB1, SERPINC1 BACE1 3298/4885ABCG2 1601/4885CACNA1H 1289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.