Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5643726 | 0.89 | CTH (0.34) | CTHDDAH1ALDH1A1 | |
| SCHEMBL5644856 | 0.85 | DDAH1 (0.36) | CTHDDAH1ALDH1A1 | |
| SCHEMBL5642370 | 0.84 | CTH (0.36) | CTHDDAH1CACNB3CACNA2D1CACNA1C | |
| SCHEMBL5642996 | 0.84 | PLA2G2A (0.36) | CTHDDAH1 | |
| SCHEMBL5643639 | 0.83 | DDAH1 (0.32) | CTHDDAH1 | |
| SCHEMBL5643993 | 0.83 | DDAH1 (0.37) | CTHDDAH1 | |
| SCHEMBL5643618 | 0.82 | DDAH1 (0.33) | CTHDDAH1 | |
| SCHEMBL5642424 | 0.82 | CTH (0.33) | CTHDDAH1 | |
| SCHEMBL5646719 | 0.82 | PLA2G2A (0.38) | DDAH1 | |
| SCHEMBL5643694 | 0.81 | CTH (0.32) | CTHDDAH1CACNB3CACNA2D1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250433-B2 | Tetrazole and oxadiazolone substituted β-amino acid derivatives | WARNER LAMBERT COMPANY LLC (US) | 2007-07-31 | — | — | US | disclosed |