Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645352 | 0.88 | HPGD (0.55) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL6357738 | 0.84 | ATM (0.56) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL5645795 | 0.83 | KCNA5 (0.55) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL5645103 | 0.82 | HPGD (0.62) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL5645008 | 0.81 | HPGD (0.57) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL6362508 | 0.80 | HPGD (0.50) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL15686619 | 0.79 | KMT2A (0.70) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL5644578 | 0.78 | GAA (0.52) | HPGDALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6357659 | 0.78 | TP53 (0.56) | HPGDALDH1A1CYP1A2KMT2A | |
| SCHEMBL6358887 | 0.76 | HPGD (0.55) | HPGDALDH1A1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |