Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645103 | 0.88 | HPGD (0.62) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL6357794 | 0.83 | TSHR (0.64) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL5644455 | 0.81 | HPGD (0.52) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL5641667 | 0.81 | GRIN1 (0.67) | HPGDALDH1A1LMNASMN1; SMN2GRIN1 | |
| SCHEMBL5645352 | 0.81 | HPGD (0.55) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL6358887 | 0.81 | HPGD (0.55) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL6358889 | 0.80 | ALDH1A1 (0.65) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL6357738 | 0.80 | ATM (0.56) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL6355073 | 0.80 | MEN1 (0.56) | HPGDALDH1A1CYP1A2POLBNPC1 | |
| SCHEMBL5860823 | 0.79 | NPC1 (0.71) | HPGDALDH1A1CYP1A2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |