Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357738 | 0.91 | ATM (0.56) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL5645352 | 0.89 | HPGD (0.55) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL6358887 | 0.89 | HPGD (0.55) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL5645008 | 0.88 | HPGD (0.57) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL5860823 | 0.84 | NPC1 (0.71) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL5644455 | 0.82 | HPGD (0.52) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL5648574 | 0.81 | LMNA (0.75) | HPGDALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL10605231 | 0.81 | POLB (0.64) | HPGDALDH1A1POLBCYP1A2NPC1 | |
| SCHEMBL6358889 | 0.81 | ALDH1A1 (0.65) | HPGDALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL6356715 | 0.80 | LMNA (0.49) | HPGDALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |