Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110723 | 1.00 | TDP1 (0.52) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL14247146 | 0.93 | MAPT (0.50) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL199359 | 0.91 | MAPT (0.52) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL29595940 | 0.91 | TDP1 (0.52) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL3990674 | 0.91 | TDP1 (0.52) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL29665784 | 0.91 | MAPT (0.52) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL8095561 | 0.89 | MAPT (0.50) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL6505797 | 0.89 | MAPT (0.50) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL8698196 | 0.89 | TDP1 (0.50) | TDP1MAPTALDH1A1MEN1POLB | |
| Acetonitrile SCHEMBL9863169 | 0.89 | TDP1 (0.47) | TDP1MAPTALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230324398-A1 | REAGENT FOR MASS SPECTROMETRY | ROCHE DIAGNOSTICS GMBH (DE) | 2023-10-12 | — | — | US | claimed |
| EP-4154010-A1 | REAGENT FOR MASS SPECTROMETRY | F. Hoffmann-La Roche AG (CH) | 2023-03-29 | — | — | EP | claimed |
| CN-115667934-A | Reagent for mass spectrometry | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| WO-2021234002-A1 | REAGENT FOR MASS SPECTROMETRY | F. HOFFMANN-LA ROCHE AG (CH) | 2021-11-25 | — | — | WO | claimed |
| CN-101968470-B | Method for separating and measuring acetylcysteine enantiomers | HUBEI SHINE STAR BIOLOG ENGINEERING CO LTD | 2013-11-20 | — | — | CN | claimed |
| CN-101788542-B | Pregabalin and separation detection method of chiral isomer thereof | SHANGHAI CHENPON PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-102375037-A | Method for separating and determining pregabalin chiral isomer by using electrophoresis-mediated microanalysis technology | SHANGHAI XIUXIN CHENPON PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-03-14 | — | — | CN | claimed |
| CN-101968470-A | Method for separating and measuring acetylcysteine enantiomers | HUBEI SHINE STAR BIOLOG ENGINEERING CO LTD | 2011-02-09 | — | — | CN | claimed |
| CN-101788542-A | Pregabalin and separation detection method of chiral isomer thereof | SHANGHAI CHENPON PHARMACEUTICA | 2010-07-28 | — | — | CN | claimed |
| CN-1786703-A | Process for separating and determining pregabalin/Lyrica chiral isomer | CHONGQING PHARMACEUTICAL INDUS (CN) | 2006-06-14 | — | — | CN | claimed |
| EP-1016405-A2 | Arylating medicaments | Radopath Pharmaceuticals International Limited (GB) | 2000-07-05 | — | — | EP | claimed |
| CN-1124012-A | Arylating medicaments | RADOPATH LTD (GB) | 1996-06-05 | — | — | CN | claimed |
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| US-20230324398-A1 | REAGENT FOR MASS SPECTROMETRY | ROCHE DIAGNOSTICS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4154010-A1 | REAGENT FOR MASS SPECTROMETRY | F. Hoffmann-La Roche AG (CH) | 2023-03-29 | — | — | EP | disclosed |
| CN-115667934-A | Reagent for mass spectrometry | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-0299921-A2 | Amphiphilic azo dyes for making ultra-thin layers with reversible colour changes | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| US-4767745-A | 1,5-DIFLUORO-2,4-DINITRO BENZENE AND 6-N-MALEIMIDOHEXANOIC ACID CHLORIDE AS COUPLING AGENTS; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1988-08-30 | — | — | US | disclosed |
| EP-0179959-A1 | Conjugates of leukotrienes with proteins | MERCK FROSST CANADA INC. (CA) | 1986-05-07 | — | — | EP | disclosed |