Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29665784 | 1.00 | MAPT (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL6505797 | 0.98 | MAPT (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL564506 | 0.91 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL30110723 | 0.91 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL14247146 | 0.89 | MAPT (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8095561 | 0.89 | MAPT (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8698196 | 0.84 | TDP1 (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7521966 | 0.84 | TSHR (0.77) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5949104 | 0.84 | TSHR (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL2315347 | 0.84 | MAPT (0.46) | MAPTTDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843639-A | 3- [7- (2-carboxyl-2-cyanovinyl) -5, 6-difluoro- [1,10] phenanthroline-4-yl ] -2-cyanoacrylate, preparation method and application thereof | 湘潭大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117820225-A | 3- (8-amino-5, 6-difluoro-4-quinolyl) -2-cyanoacrylate, and preparation method and application thereof | 湘潭大学 | 2024-04-05 | — | — | CN | claimed |
| CN-111362867-A | Mobile terminal, shell assembly, electrochromic material and preparation method thereof | 宁波祢若电子科技有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-110551072-A | quinoxaline-N 1, N 4 -dioxide derivative with DNA topoisomerase activity inhibition function, preparation method and application | UNIV HUAZHONG AGRICULTURAL | 2019-12-10 | — | — | CN | claimed |
| US-20180355099-A1 | Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-12-13 | — | — | US | claimed |
| US-6372030-B1 | INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID | XEROX CORPORATION | 2002-04-16 | — | — | US | claimed |
| US-20260097034-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LTD (HK) | 2026-04-09 | — | — | US | disclosed |
| US-12458642-B2 | Metalloenzyme inhibitor compounds | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2025-11-04 | — | — | US | disclosed |
| US-20250197420-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2025-06-19 | — | — | US | disclosed |
| EP-3848370-B1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2025-05-07 | — | — | EP | disclosed |
| EP-4219460-B1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20250011324-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC., | 2025-01-09 | — | — | US | disclosed |
| WO-2024248096-A1 | VINYLENE CROSSLINKED QUINOXALINE DERIVATIVE AND π-CONJUGATED POLYMER OBTAINED BY USING SAME | 国立大学法人 岡山大学 | 2024-12-05 | — | — | WO | disclosed |
| EP-0230946-A2 | Process for the preparation of quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230947-A1 | Halogenobenzoic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230948-A2 | Benzoylacetic acid ester derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0029658-A1 | Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12458642-B2 | Metalloenzyme inhibitor compounds | CYP11B2, CYP11B1, HSD11B2 | MAPT 2593/4885TDP1 2721/4885ALDH1A1 232/4885 |
| US-20250011324-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | TGM2, TGM3, TGM1 | MAPT 353/4885TDP1 1246/4885ALDH1A1 4148/4885 |
| US-20250197420-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCB1, PKD1 | MAPT 4827/4885TDP1 3209/4885ALDH1A1 3545/4885 |
| US-20260097034-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CPN1, TPP1, DPP4 | MAPT 2173/4885TDP1 692/4885ALDH1A1 189/4885 |
| US-20180355099-A1 | Fluorinated Benzoxadiazole-Based Donor-Acceptor Polymers for Electronic and Photonic Applications | FTO, PPOX, FOXO3 | MAPT 37/4885TDP1 956/4885ALDH1A1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.