Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500039 | 0.91 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL17580458 | 0.89 | ALDH1A1 (0.47) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29595940 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30110723 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL3990674 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL564506 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL14247146 | 0.87 | MAPT (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8095561 | 0.87 | MAPT (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL4670199 | 0.86 | TDP1 (0.62) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29665784 | 0.84 | MAPT (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522870-B2 | 2,5-disubstituted-1,4-diaminobenzenes | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2016-12-20 | — | — | US | claimed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | claimed |
| JP-63310850-A | — | — | None | — | — | JP | disclosed |
| US-20240389591-A1 | CRYSTALLINE FORMS OF METHYL 2-[2-[2-BROMO-4-FLUORO-5-[3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)PYRIMIDIN-1-YL]PHENOXY]PHENOXY]-2-METHOXY-ACETATE | BASF SE (DE) | 2024-11-28 | — | — | US | disclosed |
| CN-112513141-B | Polymer for use in electronic devices | 杜邦电子公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230157289-A1 | HERBICIDAL PHENYLURACILS | BASF SE (DE) | 2023-05-25 | — | — | US | disclosed |
| WO-2023030935-A1 | METHOD FOR CONTROLLING PPO-I RESISTANT WEEDS | BASF SE (DE) | 2023-03-09 | — | — | WO | disclosed |
| WO-2023030916-A1 | CRYSTALLINE FORMS OF METHYL 2-[2-[2-BROMO-4-FLUORO-5-[3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)PYRIMIDIN-1-YL]PHENOXY]PHENOXY]-2-METHOXY-ACETATE | BASF SE (DE) | 2023-03-09 | — | — | WO | disclosed |
| CN-115244035-A | Herbicidal phenyluracils | 巴斯夫欧洲公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112513141-A | Polymers for use in electronic devices | 杜邦电子公司 | 2021-03-16 | — | — | CN | disclosed |
| US-9522870-B2 | 2,5-disubstituted-1,4-diaminobenzenes | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2013-09-12 | — | — | US | disclosed |
| WO-1998018768-A1 | HERBICIDAL 3-(BICYCLIC NITROGEN-CONTAINING HETEROCYCLE)-SUBSTITUTED-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1998-05-07 | — | — | WO | disclosed |
| US-5661108-A | CONTROLLING PLANT GROWTH | FMC CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |
| US-5310724-A | Pre- and postemergence; plant growth regulators | FMC CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5108486-A | Herbicides | KANAGAWA CHEMICAL LABORATORY, LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| JP-S63310850-A | 2,5-DIFLUOROPHENOL DERIVATIVE | SAGAMI CHEM RES CENTER | 1988-12-19 | — | — | JP | disclosed |
| US-4725283-A | NITROBENZENE DIRECT DYES FOR HUMAN HAIR | L'OREAL (FR) | 1988-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237725-A1 | 2,5-DISUBSTITUTED-1,4-DIAMINOBENZENES | DDT, PARP2, DDX42 | TDP1 777/4885ATM 1159/4885ALDH1A1 143/4885 |
| US-20240389591-A1 | CRYSTALLINE FORMS OF METHYL 2-[2-[2-BROMO-4-FLUORO-5-[3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)PYRIMIDIN-1-YL]PHENOXY]PHENOXY]-2-METHOXY-ACETATE | PML, RCC1, MAP2 | TDP1 1717/4885ATM 2921/4885ALDH1A1 1747/4885 |
| US-20230157289-A1 | HERBICIDAL PHENYLURACILS | PFAS, DDT, DPYD | TDP1 824/4885ATM 3875/4885ALDH1A1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.