Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199359 | 0.98 | MAPT (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL29665784 | 0.98 | MAPT (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL30110723 | 0.89 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL564506 | 0.89 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL14247146 | 0.87 | MAPT (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8095561 | 0.87 | MAPT (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3990674 | 0.84 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL29595940 | 0.84 | TDP1 (0.52) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8698196 | 0.83 | TDP1 (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7521966 | 0.82 | TSHR (0.77) | MAPTTDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | disclosed |