Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | AADAC | P22760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644117 | 0.85 | FBP1 (0.43) | ARCYP3A4PGRNR3C1NR3C2 | |
| SCHEMBL3654876 | 0.81 | NR3C1 (0.53) | ARPGRNR3C1NR3C2 | |
| SCHEMBL5644090 | 0.81 | ATM (0.40) | ARCYP3A4PGRATMTDP1 | |
| SCHEMBL5865883 | 0.79 | FBP1 (0.40) | ARCYP3A4PGRATMTDP1 | |
| SCHEMBL1775956 | 0.78 | NR3C1 (0.67) | PGRNR3C1NR3C2 | |
| SCHEMBL1775018 | 0.78 | NR3C1 (0.67) | PGRNR3C1NR3C2 | |
| SCHEMBL1775343 | 0.78 | NR3C1 (0.67) | PGRNR3C1NR3C2 | |
| SCHEMBL13767407 | 0.74 | NR3C1 (0.48) | PGRNR3C1NR3C2 | |
| SCHEMBL5642551 | 0.74 | NR3C1 (0.77) | ARPGRNR3C1NR3C2 | |
| SCHEMBL15074725 | 0.74 | ATM (0.56) | ARCYP3A4PGRATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166592-B2 | Antiinflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-01-23 | — | — | US | disclosed |
| US-7129270-B2 | Nonsteroidal antiinflammatory agents | Schėring AG (DE) | 2006-10-31 | — | — | US | disclosed |
| US-20060040933-A1 | Nonsteroidal antiinflammatory agents | JAROCH STEFAN | 2006-02-23 | — | — | US | disclosed |
| US-20040254249-A1 | Nonsteroidal antiinflammatory agents | JAROCH STEFAN (DE) | 2004-12-16 | — | — | US | disclosed |
| US-6777409-B2 | FOR THERAPY OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT PATENTS (DE) | 2004-08-17 | — | — | US | disclosed |
| CN-1444570-A | Non-steroidal anti-inflammatory drugs | SCHERING AG (DE) | 2003-09-24 | — | — | CN | disclosed |
| EP-1309571-A1 | NON-STEROIDAL INFLAMMATION INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-20020077356-A1 | Nonsteroidal antiinflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | US | disclosed |
| WO-2002010143-A1 | NON-STEROIDAL INFLAMMATION INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077356-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGES2, PTGES | AR 2971/4885CYP3A4 441/4885PGR 1776/4885 |
| US-20060040933-A1 | Nonsteroidal antiinflammatory agents | PTGES, PTGES2, PTGS1 | AR 3082/4885CYP3A4 821/4885PGR 1229/4885 |
| US-20040254249-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGER1, PTGES2 | AR 4037/4885CYP3A4 516/4885PGR 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.