SCHEMBL5645602

SCHEMBL5645602

COCCCNC1CC(C)(C)N(c2nc(Cl)nc(N3C(C)(C)CC(NCCCOC)CC3(C)C)n2)C(C)(C)C1

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCNK O75909 1/20 0.30
CDK9 P50750 1/20 0.30
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39151 0.85
SCHEMBL6934625 0.83
SCHEMBL9760359 0.77 FPR3 (0.30)
SCHEMBL5645604 0.72
SCHEMBL6050522 0.70 VCP (0.32)
SCHEMBL9250598 0.69 FLT3 (0.33)
SCHEMBL9371866 0.69 TSHR (0.42) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL9152729 0.68
SCHEMBL5650386 0.68
SCHEMBL9371300 0.68 ALDH1A1 (0.46) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297734-B2 Process for preparing synergistic stabilizer mixtures CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-11-20 US disclosed
EP-1474471-B8 PROCESS FOR PREPARING A SYNERGISTIC STABILIZER MIXTURE CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-10-04 EP disclosed
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US disclosed
EP-0718357-B1 Flame-resistant moulding composition having improved light stability CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-07-19 EP disclosed
EP-1474471-B1 SELECTIVE OXIDATION OF SODIUM SULFIDE IN KRAFT COOKING LIQUORS CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-05-03 EP disclosed
US-20050250889-A1 Synergistc stabilizer composition for color stable pigmented thermophastic polymers in prolonged contact with water CLARIANT FINANCE (BVI) LIMITED (VG) 2005-11-10 US disclosed
US-20050228086-A1 Selective oxidation of sodium sulfide in kraft cooking liquors CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2005-10-13 US disclosed
EP-1417257-B1 PHENOLFREE STABILIZATION OF POLYOLEFINS CLARIANT FINANCE BVI LTD (VG) 2005-02-09 EP disclosed
EP-1474471-A1 SELECTIVE OXIDATION OF SODIUM SULFIDE IN KRAFT COOKING LIQUORS Clariant GmbH (DE) 2004-11-10 EP disclosed
EP-1268644-B1 SYNERGISTIC STABILIZER COMPOSITIONS FOR THERMOPLASTIC POLYMERS IN PROLONGED CONTACT WITH WATER CLARIANT FINANCE BVI LTD (VG) 2004-10-20 EP disclosed
US-5985961-A POLYESTER MONOFILAMENTS OF COPOLYESTERS, CARBON BLACK, ANTIOXIDANTS JOHNS MANVILLE INTERNATIONAL, INC. (US) 1999-11-16 US disclosed
EP-0885924-A2 Improved monofilament HOECHST CELANESE CORPORATION (US) 1998-12-23 EP disclosed
US-5852159-A Plastic with reduced sulfur uptake rate HOECHST AKTIENGESELLSCHAFT (DE) 1998-12-22 US disclosed
EP-0690060-B1 Polyalkylpiperidine compounds CLARIANT GMBH (DE) 1998-09-09 EP disclosed
US-5633378-A STABILIZER FOR POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
EP-0742254-A2 Resin having reduced rate of sulfur acceptance HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-13 EP disclosed
US-5550234-A STABILIZERS WITH VERY LOW VOLATILITY AT ELEVATED TEMPERATURES HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
EP-0718357-A2 Flame-resistant moulding composition having improved light stability HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-26 EP disclosed
EP-0705836-A1 Polyalkylpiperidine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-10 EP disclosed
EP-0690060-A1 Two crystal modifications of a diketopyrrolopyrrole HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-03 EP disclosed