SCHEMBL564570

SCHEMBL564570

CCO[SiH](CCCC(C)N)OCC

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.46
TP53 P04637 1/20 0.38
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819523 0.86 OPRM1 (0.39) OPRM1TP53ALDH1A1
SCHEMBL25300792 0.84 LMNA (0.35)
SCHEMBL1606772 0.81
SCHEMBL25267372 0.79
SCHEMBL28519141 0.79 OPRM1 (0.42) OPRM1TP53ALDH1A1TDP1
SCHEMBL9442193 0.77 LMNA (0.39) OPRM1
SCHEMBL703802 0.77
SCHEMBL703482 0.77
SCHEMBL23579493 0.77 ANPEP (0.30)
SCHEMBL637874 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2217827-B1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORP (US) 2020-06-03 EP disclosed
US-9529286-B2 Antioxidants for overcoat layers and methods for making the same XEROX CORPORATION (US) 2016-12-27 US disclosed
US-20160154327-A1 CHARGE TRANSPORT LAYER FOR IMAGING DEVICE XEROX CORPORATION 2016-06-02 US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-9023561-B1 Charge transport layer comprising silicone ester compounds XEROX CORPORATION (US) 2015-05-05 US disclosed
US-20150102529-A1 ANTIOXIDANTS FOR OVERCOAT LAYERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-04-16 US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 US disclosed
US-8983356-B2 Image forming apparatus XEROX CORPORATION (US) 2015-03-17 US disclosed
US-8940105-B2 Sulfonamide-doped undercoat for imaging device XEROX CORPORATION (US) 2015-01-27 US disclosed
US-5698359-A ELECTROPHOTOGRAPHIC IMAGING MEMBERS; CHARGE GENERATING LAYER OF HYDROXYGALLIUM PHTHALOCYANINE PARTICLES; CHARGE TRANSPORTING POLYMER COMPRISING ACTIVE ARYLAMINE MOIETIES XEROX CORPORATION (US) 1997-12-16 US disclosed
US-5681391-A Immersion coating apparatus XEROX CORPORATION (US) 1997-10-28 US disclosed
US-5492785-A METAL GROUND PLANE LAYER CONTAINING ZIRCONIUM, SILOXANE HOLE BLOCKING LAYER, POLYARYLATE ADHESIVE LAYER, CHARGE GENERATING LAYER OF BENZIMIDAZOLE PERYLENE PARTICLES DISPERSED IN POLYCARBONATE BINDER, HOLE TRANSPORT LAYER XEROX CORPORATION (US) 1996-02-20 US disclosed
US-5283143-A Electrophotographic imaging member containing arylamine terpolymers with CF3 substituted moieties XEROX CORPORATION (US) 1994-02-01 US disclosed
EP-0295115-B1 ARYLAMINE COMPOUNDS XEROX CORPORATION (US) 1992-06-24 EP disclosed
US-5030532-A Electrophotographic imaging member utilizing polyarylamine polymers XEROX CORPORATION (US) 1991-07-09 US disclosed
US-5028502-A Charge Transport Layer Containing Polystyrene Film Forming Binder And An Aromatic Diamine Or Hydrazone Compound XEROX CORPORATION (US) 1991-07-02 US disclosed
WO-1990001507-A1 MOISTURE-CURING HOT-MELT ADHESIVES CONTAINING TERMINAL ALKOXYSILANE GROUPS AND THEIR USE AS ADHESIVES AND SEALANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-22 WO disclosed
EP-0354472-A1 Alkoxysilane-terminated moisture-curable hot melt adhesives and their use as adhesive and sealant masses Henkel Kommanditgesellschaft auf Aktien (DE) 1990-02-14 EP disclosed
US-4871634-A Electrophotographic elements using hydroxy functionalized arylamine compounds XEROX CORPORATION (US) 1989-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150102529-A1 ANTIOXIDANTS FOR OVERCOAT LAYERS AND METHODS FOR MAKING THE SAME LPO, MGMT, ABAT OPRM1 3369/4885TP53 1218/4885ALDH1A1 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.