Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645944 | 1.00 | ACHE (0.35) | ACHEKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8522688 | 0.81 | MAPT (0.34) | ACHEKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL1387238 | 0.77 | HIF1A (0.34) | ACHEKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9000591 | 0.76 | PTGS1 (0.34) | ACHE | |
| SCHEMBL9000584 | 0.76 | PTGS1 (0.34) | ACHE | |
| SCHEMBL1387468 | 0.72 | HIF1A (0.36) | ACHEKMT2AMEN1NPC1PLA2G2A | |
| SCHEMBL8667535 | 0.72 | HTT (0.42) | KMT2AMEN1NPC1ALDH1A1KDM4E | |
| SCHEMBL8667533 | 0.72 | HTT (0.42) | KMT2AMEN1NPC1ALDH1A1KDM4E | |
| SCHEMBL1333813 | 0.69 | HIF1A (0.34) | ACHEPLA2G2AHSP90AA1ALDH1A1KDM4E | |
| SCHEMBL1387201 | 0.69 | POLB (0.40) | KMT2AMEN1HSP90AA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| US-5578252-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1996-11-26 | — | — | US | claimed |
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| US-5578252-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1996-11-26 | — | — | US | disclosed |