Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218266 | 0.87 | GRM4 (0.38) | LMNAPOLBHSD11B1SLC1A2SLC1A1 | |
| SCHEMBL21313418 | 0.80 | HSD11B1 (0.33) | LMNAPOLBHSD11B1CES2CES1 | |
| SCHEMBL5644047 | 0.78 | HSD11B1 (0.31) | LMNAPOLBHSD11B1GRM2CYP2C19 | |
| SCHEMBL5647079 | 0.78 | SLC1A2 (0.33) | LMNAPOLBHSD11B1SLC1A2SLC1A1 | |
| SCHEMBL5646787 | 0.76 | HSD11B1 (0.30) | LMNAPOLBHSD11B1 | |
| SCHEMBL5651667 | 0.74 | SLC1A2 (0.30) | SLC1A2SLC1A1 | |
| Cyclopentane SCHEMBL6061198 | 0.74 | LMNA (0.38) | LMNAPOLBHSD11B1SLC1A2SLC1A1 | |
| SCHEMBL2113419 | 0.74 | HSD11B1 (0.32) | LMNAHSD11B1CES2CES1GRM2 | |
| SCHEMBL6359438 | 0.74 | GRM2 (0.33) | LMNASLC1A2SLC1A1GRM2GRM3 | |
| SCHEMBL3482751 | 0.74 | HSD11B1 (0.32) | LMNAHSD11B1CES2CES1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271282-B1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |