SCHEMBL2113419

SCHEMBL2113419

O=C(O)C1CCCCC(C(=O)O)(C2CCCCCC2)C1(C(=O)O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.32
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
GRM2 Q14416 2/20 0.30
GRM3 Q14832 2/20 0.30
GRM4 Q14833 2/20 0.30
CYP1A2 P05177 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
GRM5 P41594 1/20 0.30
MTOR P42345 1/20 0.30
GRM1 Q13255 1/20 0.30
PLCB1 Q9NQ66 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482751 1.00 HSD11B1 (0.32) HSD11B1LMNATSHRCES2CES1
SCHEMBL3684320 0.97 CES2 (0.30) HSD11B1LMNATSHRCES2CES1
SCHEMBL16026846 0.89 SLC1A2 (0.33) LMNATSHRGRM2GRM3GRM4
SCHEMBL25218266 0.81 GRM4 (0.38) HSD11B1LMNATSHRCES2CES1
SCHEMBL3123620 0.81 GRM2 (0.31) LMNATSHRGRM2GRM3GRM4
SCHEMBL6359435 0.78
SCHEMBL21313418 0.75 HSD11B1 (0.33) HSD11B1LMNATSHRCES2CES1
SCHEMBL210214 0.75 CES2 (0.36) HSD11B1LMNATSHRCES2CES1
SCHEMBL5645968 0.74 LMNA (0.36) HSD11B1LMNATSHRCES2CES1
SCHEMBL17386420 0.73 HSD11B1 (0.34) HSD11B1LMNATSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874418-A Polyimide, polyamic acid, resin solution, coating agent, and polyimide film 引能仕株式会社 2021-12-31 CN disclosed
CN-106978195-B Liquid crystal alignment film, liquid crystal display assembly and manufacturing method thereof 奇美实业股份有限公司 2020-12-01 CN disclosed
WO-2019181699-A1 RESIN, RESIN PRECURSOR AND RESIN PRECURSOR SOLUTION JXTGエネルギー株式会社 2019-09-26 WO disclosed
CN-102707570-B Photosensitive resin composition, spacer and liquid crystal display element containing the same CHI MEI CORP 2014-08-06 CN disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
CN-102707570-A Photosensitive resin composition, spacer and liquid crystal display element containing the same CHI MEI CORP 2012-10-03 CN disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20120094015-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-04-19 US disclosed
CN-101614912-B Liquid crystal aligning agent and method for producing liquid crystal alignment film formed by using the same CHIMEI CORP 2011-01-05 CN disclosed
US-7373060-B2 Optical waveguide using polymer composed of silsesquioxane derivative CHISSO CORPORATION (JP) 2008-05-13 US disclosed
CN-101082771-A Photosensitive resin composition for color filter CHI MEI CORP (CN) 2007-12-05 CN disclosed
US-20070238047-A1 Photosensitive resin composition for color filters CHI-MEI CORPORATION 2007-10-11 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20060204192-A1 Optical waveguide using polymer composed of silsesquioxane derivative JNC CORPORATION (JP) 2006-09-14 US disclosed
US-20060204680-A1 Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same JNC CORPORATION (JP) 2006-09-14 US disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US disclosed
US-6685997-B1 SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING CHISSO CORPORATION (JP) 2004-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 HSD11B1 1876/4885LMNA 280/4885TSHR 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.