Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30041313 | 0.87 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL1437359 | 0.87 | IDH1 (0.37) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL31078226 | 0.87 | IDH1 (0.37) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL906764 | 0.87 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL21296390 | 0.83 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL29427057 | 0.82 | HTR7 (0.35) | GABRA1GABRG2GABRB3GABRA3IDH1 | |
| SCHEMBL37428 | 0.82 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL534247 | 0.82 | HTR7 (0.35) | GABRA1GABRG2GABRB3GABRA3IDH1 | |
| SCHEMBL955898 | 0.82 | PGK1 (0.38) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL2757632 | 0.82 | HTR7 (0.35) | GABRA1GABRG2GABRB3GABRA3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029539-B2 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-1678190-B1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| EP-1678190-B1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| EP-1678190-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | Merck Patent GmbH (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042550-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2005-05-12 | — | — | WO | disclosed |